Beyond fibrinolysis: the confounding role of Lp (a) in thrombosis
MB Boffa - Atherosclerosis, 2022 - Elsevier
Elevated plasma concentrations of lipoprotein (a)(Lp (a)) are a causal risk factor for the
development of atherothrombotic disorders including coronary heart disease. However, the …
development of atherothrombotic disorders including coronary heart disease. However, the …
Oxidized phospholipid modification of lipoprotein (a): epidemiology, biochemistry and pathophysiology
ML Koschinsky, MB Boffa - Atherosclerosis, 2022 - Elsevier
Oxidized phospholipids (OxPL) are key mediators of the pro-atherosclerotic effects of
oxidized lipoproteins. They are particularly important for the pathogenicity of lipoprotein …
oxidized lipoproteins. They are particularly important for the pathogenicity of lipoprotein …
Low circulatory levels of total cholesterol, HDL-C and LDL-C are associated with death of patients with sepsis and critical illness: systematic review, meta-analysis …
R Taylor, C Zhang, D George, S Kotecha… - …, 2024 - thelancet.com
Background Mechanistic studies have established a biological role of sterol metabolism in
infection and immunity with clinical data linking deranged cholesterol metabolism during …
infection and immunity with clinical data linking deranged cholesterol metabolism during …
[HTML][HTML] Daring to dream: Targeting lipoprotein (a) as a causal and risk-enhancing factor
ML Koschinsky, ESG Stroes, F Kronenberg - Pharmacological Research, 2023 - Elsevier
Abstract Lipoprotein (a)[Lp (a)], a distinct lipoprotein class, has become a major focus for
cardiovascular research. This review is written in light of the recent guideline and consensus …
cardiovascular research. This review is written in light of the recent guideline and consensus …
[HTML][HTML] Non-genetic influences on lipoprotein (a) concentrations
B Enkhmaa, L Berglund - Atherosclerosis, 2022 - Elsevier
An elevated level of lipoprotein (a)[Lp (a)] is a genetically regulated, independent, causal
risk factor for cardiovascular disease. However, the extensive variability in Lp (a) levels …
risk factor for cardiovascular disease. However, the extensive variability in Lp (a) levels …
Lipoprotein (a) and inflammation-pathophysiological links and clinical implications for cardiovascular disease
S Simantiris, AS Antonopoulos, C Papastamos… - Journal of Clinical …, 2023 - Elsevier
The role of lipoprotein (a)(Lp [a]) as a significant and possibly causal cardiovascular disease
(CVD) risk factor has been well established. Many studies, mostly experimental, have …
(CVD) risk factor has been well established. Many studies, mostly experimental, have …
[HTML][HTML] The long journey of lipoprotein (a) from cardiovascular curiosity to therapeutic target
ML Koschinsky, F Kronenberg - Atherosclerosis, 2022 - Elsevier
Atherosclerosis, as the official journal of the European Atherosclerosis Society (EAS),
decided that it would be timely to publish a comprehensive collection of review articles on …
decided that it would be timely to publish a comprehensive collection of review articles on …
[HTML][HTML] Is there a benefit of aspirin therapy for primary prevention to reduce the risk of atherosclerotic cardiovascular disease in patients with elevated Lipoprotein (a) …
MH Sukkari, B Al-Bast, R Al Tamimi, W Giesing… - American Journal of …, 2023 - Elsevier
Aspirin has long been recognized as a beneficial treatment for atherosclerotic
cardiovascular disease (ASCVD) due to its antiplatelet effects. However, there is a need to …
cardiovascular disease (ASCVD) due to its antiplatelet effects. However, there is a need to …
[HTML][HTML] Lipoprotein (a), Interleukin-6 inhibitors, and atherosclerotic cardiovascular disease: Is there an association?
Background and aims Lipoprotein (a)[Lp (a)] and interleuking-6 (IL-6), an inflammation
biomarker, have been established as distinct targets of the residual atherosclerotic …
biomarker, have been established as distinct targets of the residual atherosclerotic …
[HTML][HTML] Elevated lipoprotein (a) levels and atrial fibrillation: a systematic review
W Masson, L Barbagelata, JP Nogueira… - Journal of Lipid and …, 2023 - ncbi.nlm.nih.gov
Objective The role of lipoprotein (a)(Lp [a]) as a possibly causal risk factor for atherosclerotic
cardiovascular disease has been well established. However, the clinical evidence regarding …
cardiovascular disease has been well established. However, the clinical evidence regarding …