Neuroinflammation: a signature or a cause of epilepsy?

E Pracucci, V Pillai, D Lamers, R Parra… - International journal of …, 2021 - mdpi.com
Epilepsy can be both a primary pathology and a secondary effect of many neurological
conditions. Many papers show that neuroinflammation is a product of epilepsy, and that in …

Safe surgery for glioblastoma: Recent advances and modern challenges

JKW Gerritsen, MLD Broekman… - Neuro-oncology …, 2022 - academic.oup.com
One of the major challenges during glioblastoma surgery is balancing between maximizing
extent of resection and preventing neurological deficits. Several surgical techniques and …

MAPK signaling pathway-based glioma subtypes, machine-learning risk model, and key hub proteins identification

H Liu, T Tang - Scientific Reports, 2023 - nature.com
An early diagnosis and precise prognosis are critical for the treatment of glioma. The
mitogen‑activated protein kinase (MAPK) signaling pathway potentially affects glioma, but …

[HTML][HTML] Systems Biology and Bioinformatics approach to Identify blood based signatures molecules and drug targets of patient with COVID-19

MI Hasan, MH Rahman, MB Islam, MZ Islam… - Informatics in Medicine …, 2022 - Elsevier
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection results in the
development of a highly contagious respiratory ailment known as new coronavirus disease …

Discriminating pseudoprogression and true progression in diffuse infiltrating glioma using multi-parametric MRI data through deep learning

J Lee, N Wang, S Turk, S Mohammed, R Lobo, J Kim… - Scientific reports, 2020 - nature.com
Differentiating pseudoprogression from true tumor progression has become a significant
challenge in follow-up of diffuse infiltrating gliomas, particularly high grade, which leads to a …

Clinical implementation of artificial intelligence in neuroradiology with development of a novel workflow-efficient picture archiving and communication system-based …

M Aboian, K Bousabarah, E Kazarian, T Zeevi… - Frontiers in …, 2022 - frontiersin.org
Purpose Personalized interpretation of medical images is critical for optimum patient care,
but current tools available to physicians to perform quantitative analysis of patient's medical …

Saponins as cytotoxic agents: An update (2010–2021). Part II—Triterpene saponins

I Podolak, K Grabowska, D Sobolewska… - Phytochemistry …, 2023 - Springer
Saponins make up an important group of natural glycosidic compounds which are
distinguished by triterpene or steroidal aglycone. Although widely distributed in terrestrial …

Bioinformatics and machine learning methodologies to identify the effects of central nervous system disorders on glioblastoma progression

MH Rahman, HK Rana, S Peng, X Hu… - Briefings in …, 2021 - academic.oup.com
Glioblastoma (GBM) is a common malignant brain tumor which often presents as a
comorbidity with central nervous system (CNS) disorders. Both CNS disorders and GBM …

Cellular senescence in glioma

R Chojak, J Fares, E Petrosyan, MS Lesniak - Journal of Neuro-Oncology, 2023 - Springer
Introduction Glioma is the most common primary brain tumor and is often associated with
treatment resistance and poor prognosis. Standard treatment typically involves radiotherapy …

Tumor cell and immune cell profiles in primary human glioblastoma: Impact on patient outcome

M González‐Tablas Pimenta, Á Otero… - Brain …, 2021 - Wiley Online Library
The distribution and role of tumor‐infiltrating leucocytes in glioblastoma (GBM) remain
largely unknown. Here, we investigated the cellular composition of 55 primary (adult) GBM …