Bioinspired oral delivery devices
Oral administration is a widespread and convenient drug delivery approach. However, oral
delivery can be affected by the complex digestive tract environment, including irregular …
delivery can be affected by the complex digestive tract environment, including irregular …
Progress and prospects of polysaccharide-based nanocarriers for oral delivery of proteins/peptides
H Yuan, C Guo, L Liu, L Zhao, Y Zhang, T Yin… - Carbohydrate …, 2023 - Elsevier
The oral route has long been recognized as the most preferred route for drug delivery as it
offers high patient compliance and requires minimal expertise. Unlike small molecule drugs …
offers high patient compliance and requires minimal expertise. Unlike small molecule drugs …
Nanoparticles exhibiting virus-mimic surface topology for enhanced oral delivery
Z Sang, L Xu, R Ding, M Wang, X Yang, X Li… - Nature …, 2023 - nature.com
The oral delivery of nano-drug delivery systems (Nano-DDS) remains a challenge. Taking
inspirations from viruses, here we construct core–shell mesoporous silica nanoparticles …
inspirations from viruses, here we construct core–shell mesoporous silica nanoparticles …
Zwitterionic polymers: addressing the barriers for drug delivery
M Li, W Zhang, J Li, Y Qi, C Peng, N Wang, H Fan… - Chinese Chemical …, 2023 - Elsevier
Nanocarriers play an important role in drug delivery for disease treatment. However,
nanocarriers face a series of physiological barriers after administration such as blood …
nanocarriers face a series of physiological barriers after administration such as blood …
Legume-derived bioactive peptides in type 2 diabetes: opportunities and challenges
K Hu, H Huang, H Li, Y Wei, C Yao - Nutrients, 2023 - mdpi.com
Diabetes mellitus is a complex disorder characterized by insufficient insulin production or
insulin resistance, which results in a lifelong dependence on glucose-lowering drugs for …
insulin resistance, which results in a lifelong dependence on glucose-lowering drugs for …
Oral nanomedicine biointeractions in the gastrointestinal tract in health and disease
Oral administration is the preferred route of administration based on the convenience for and
compliance of the patient. Oral nanomedicines have been developed to overcome the …
compliance of the patient. Oral nanomedicines have been developed to overcome the …
Is polydopamine beneficial for cells on the modified surface?
Y Yu, X Wang, Y Zhu, Y He, H Xue… - Regenerative …, 2022 - academic.oup.com
Since the pioneering work of Messersmith's group discovering that polydopamine (PDA) can
serve to adhere to many types of materials, the PDA coating has, as a biomimetic approach …
serve to adhere to many types of materials, the PDA coating has, as a biomimetic approach …
Challenges and opportunities in delivering oral peptides and proteins
H Peng, J Wang, J Chen, Y Peng, X Wang… - Expert opinion on …, 2023 - Taylor & Francis
Introduction Rapid advances in bioengineering enable the use of complex proteins as
therapeutic agents to treat diseases. Compared with conventional small molecule drugs …
therapeutic agents to treat diseases. Compared with conventional small molecule drugs …
Advances in surface-modified nanometal-organic frameworks for drug delivery
J Li, H Peng, W Ji, D Lu, N Wang, C Peng… - International Journal of …, 2023 - Elsevier
Nanometal-organic frameworks (NMOFs) are porous network structures composed of metal
ions or metal clusters through self-assembly. NMOFs have been considered as a promising …
ions or metal clusters through self-assembly. NMOFs have been considered as a promising …
Fat fighting liraglutide based nano-formulation to reverse obesity: design, development and animal trials
Obesity is a metabolic disease, which is one of the major causes of morbidity and mortality,
where therapeutic options are limited. Treatment of obesity is necessary as it is associated …
where therapeutic options are limited. Treatment of obesity is necessary as it is associated …