For tissue engineering applications, scaffolds should be porous to enable rapid nutrient and
oxygen transfer while providing a three-dimensional (3D) microenvironment for the …

Alginates comprise a unique–and at the same time-diverse family of polysaccharides that
allows fabrication of a variety of biomaterials suitable for tissue engineering. This is reflected …

Human embryonic stem cells have been defined as self-renewing cells that can give rise to
many types of cells of the body. How and whether these cells can be manipulated to replace …

The extracellular microenvironment plays a significant role in controlling cellular behavior.
Identification of appropriate biomaterials that support cellular attachment, proliferation and …

Combining stem cells with biomaterial scaffolds serves as a promising strategy for
engineering tissues for both in vitro and in vivo applications. This updated review details …

The self-renewal and differentiation of human pluripotent stem cells (hPSCs) have typically
been studied in flat, two-dimensional (2D) environments. In this Perspective, we argue that …

Stem cells have emerged as the starting material of choice for bioprocesses to produce cells
and tissues to treat degenerative, genetic, and immunological disease. Translating the …

Pluripotent stem cells have the capacity to self renew and to differentiate to cells of the three
somatic germ layers that comprise an organism. Embryonic stem cells are the most studied …

This review focuses on vascularization and strategies involved in its evaluation and
modulation. Clinical issues associated with engineered tissues of an atomically relevant size …

Stem cells play increasingly prominent roles in tissue engineering and regenerative
medicine. Pluripotent embryonic stem (ES) cells theoretically allow every cell type in the …