Nutraceutical boom in cancer: inside the labyrinth of reactive oxygen species
M Calvani, A Pasha, C Favre - International journal of molecular sciences, 2020 - mdpi.com
In recent years, epidemiological studies have shown that food is a very powerful means for
maintaining a state of well-being and for health prevention. Many degenerative, autoimmune …
maintaining a state of well-being and for health prevention. Many degenerative, autoimmune …
Inhibiting DNA methylation by 5-Aza-2′-deoxycytidine ameliorates atherosclerosis through suppressing macrophage inflammation
Inflammation marks all stages of atherogenesis. DNA hypermethylation in the whole
genome or specific genes is associated with inflammation and cardiovascular diseases …
genome or specific genes is associated with inflammation and cardiovascular diseases …
Anticancer effects of lactoferrin: Underlying mechanisms and future trends in cancer therapy
Y Zhang, CF Lima, LR Rodrigues - Nutrition reviews, 2014 - academic.oup.com
Lactoferrin has been widely studied over the last 70 years, and its role in diverse biological
functions is now well known and generally accepted by the scientific community. Usually …
functions is now well known and generally accepted by the scientific community. Usually …
Dietary intervention modifies DNA methylation age assessed by the epigenetic clock
Scope Alterations in DNA methylation patterns are correlated with aging, environmental
exposures, and disease pathophysiology; the possibility of reverting or preventing these …
exposures, and disease pathophysiology; the possibility of reverting or preventing these …
DNMT1-PPARγ pathway in macrophages regulates chronic inflammation and atherosclerosis development in mice
J Yu, Y Qiu, J Yang, S Bian, G Chen, M Deng, H Kang… - Scientific reports, 2016 - nature.com
The DNA methyltransferase-mediated proinflammatory activation of macrophages is
causally linked to the development of atherosclerosis (AS). However, the role of DNMT1, a …
causally linked to the development of atherosclerosis (AS). However, the role of DNMT1, a …
Detection of colorectal cancer in urine using DNA methylation analysis
Colorectal cancer (CRC) is the second leading cause for cancer-related death globally.
Clinically, there is an urgent need for non-invasive CRC detection. This study assessed the …
Clinically, there is an urgent need for non-invasive CRC detection. This study assessed the …
Epigenetic alterations in the breast: Implications for breast cancer detection, prognosis and treatment
AM Dworkin, THM Huang, AE Toland - Seminars in cancer biology, 2009 - Elsevier
Epigenetic alterations of the genome such as DNA promoter methylation and chromatin
remodeling play an important role in tumorigenesis. Recent findings indicate epigenetic …
remodeling play an important role in tumorigenesis. Recent findings indicate epigenetic …
Effect of aberrant DNA methylation on cancer stem cell properties
DNA methylation, as an epigenetic mechanism, occurs by adding a methyl group of
cytosines in position 5 by DNA methyltransferases and has essential roles in cellular …
cytosines in position 5 by DNA methyltransferases and has essential roles in cellular …
[HTML][HTML] Novel epigenetic therapeutic strategies and targets in cancer
The critical role of dysregulated epigenetic pathways in cancer genesis, development, and
therapy has typically been established as a result of scientific and technical innovations in …
therapy has typically been established as a result of scientific and technical innovations in …
Aberrant DNA and RNA methylation occur in spinal cord and skeletal muscle of human SOD1 mouse models of ALS and in human ALS: targeting DNA methylation is …
LJ Martin, DA Adams, MV Niedzwiecki, M Wong - Cells, 2022 - mdpi.com
Amyotrophic lateral sclerosis (ALS) is a fatal disease. Skeletal muscles and motor neurons
(MNs) degenerate. ALS is a complex disease involving many genes in multiple tissues, the …
(MNs) degenerate. ALS is a complex disease involving many genes in multiple tissues, the …