DNA-methyltransferase-3B (DNMT3B) may play an oncogenic role during tumorigenesis,
and its genetic variants have been reportedly to be associated with risk of several cancers …

Trihalomethanes (THM) are undesired disinfection byproducts (DBPs) formed during water
treatment. Mice exposed to DBPs showed global DNA hypomethylation and c-myc and c-jun …

Receptor tyrosine kinase (RTK) signaling cascades coordinate intracellular signaling in
response to growth factors, chemokines, and other extracellular stimuli to control …

Background Although aberrant DNA methyltransferase 3a (DNMT3a) expression is
important to the tumorigenesis of pancreatic ductal adenocarcinoma (PDAC), the role of …

The abnormality of DNA methylation is involved in tumour progression, and thus has a
modulating effect on clinical outcome of cancer patients. In this study, we measured the …

S100 proteins are small, calcium-binding proteins whose genes are localized in a cluster on
human chromosome 1. Through their ability to interact with various protein partners in a …

We investigated the expression and promoter methylation of dbpA in human hepatocellular
carcinoma (HCC) and examined their correlation with clinicopathological features. In 96 …

In the past few years, immunotherapy of tumors has become an extensive research hotspot,
and the value of IKZF family genes in the tumor microenvironment has also been …

This study explored the prognostic and therapeutic potentials of multiple Proteasome 26S
Subunit, ATPase (PSMC) family of genes (PSMC1-5) in lung adenocarcinoma (LUAD) …

A decrease in ten-eleven translocation 1 (TET1) transcript and 5-Hydroxymethylcytosine
(5hmC) levels has recently been demonstrated in primary gastric cancer (GC). However …