Effect of DNA methylation on the osteogenic differentiation of mesenchymal stem cells: concise review

Z Lai, Q Shu, Y Song, A Tang, J Tian - Frontiers in Genetics, 2024 - frontiersin.org
Mesenchymal stem cells (MSCs) have promising potential for bone tissue engineering in
bone healing and regeneration. They are regarded as such due to their capacity for self …

[HTML][HTML] Role of epigenetic alterations in the pathogenesis of Barrett's esophagus and esophageal adenocarcinoma

A Agarwal, R Polineni, Z Hussein, I Vigoda… - … journal of clinical and …, 2012 - ncbi.nlm.nih.gov
Barrett's esophagus, a pre-malignant condition that can lead to esophageal
adenocarcinoma, is characterized by histological changes in the normal squamous …

Fat10 is an epigenetic marker for liver preneoplasia in a drug-primed mouse model of tumorigenesis

J Oliva, F Bardag-Gorce, BA French, J Li… - … and molecular pathology, 2008 - Elsevier
There is clinical evidence that chronic liver diseases in which MDBs (Mallory Denk Bodies)
form progress to hepatocellular carcinoma. The present study provides evidence that links …

DNA methylation biphasically regulates 3T3-L1 preadipocyte differentiation

X Yang, R Wu, W Shan, L Yu, B Xue… - Molecular …, 2016 - academic.oup.com
Better understanding the mechanisms underlying adipogenesis may provide novel
therapeutic targets in the treatment of obesity. Most studies investigating the mechanisms …

Genomic instability and carcinogenesis of heavy charged particles radiation: Clinical and environmental implications

K Mortezaee, M Najafi, B Farhood, A Ahmadi… - Medicina, 2019 - mdpi.com
One of the uses of ionizing radiation is in cancer treatment. The use of heavy charged
particles for treatment has been introduced in recent decades because of their priority for …

A Meta‐Analysis of the Association between DNMT1 Polymorphisms and Cancer Risk

H Li, J Liu, L Sun, Y Yuan - BioMed Research International, 2017 - Wiley Online Library
Previous studies have examined the associations of DNA methyltransferase 1 (DNMT1)
polymorphisms, including single nucleotide polymorphisms rs16999593 (T/C), rs2228611 …

TET upregulation leads to 5-hydroxymethylation enrichment in hepatoblastoma

MP Rivas, TFM Aguiar, GR Fernandes… - Frontiers in …, 2019 - frontiersin.org
Hepatoblastoma is an embryonal liver tumor carrying few genetic alterations. We previously
disclosed in hepatoblastomas a genome-wide methylation dysfunction, characterized by …

Zhizi-Chuanxiong herb pair alleviates atherosclerosis progression in ApoE−/− mice by promoting the methylation of FGFR3 to inhibit MAPK/ERK-mediated apoptosis

Y Zhang, D Li, Z Jia, J Mei, Y Wang, Y Zhang… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Gardenia Fructus (Gardenia jasminoides Ellis,
Zhizi) and Chuanxiong Rhizoma (Ligusticum chuanxiong Hort., Chuanxiong) are both …

Folate and choline metabolism gene variants and development of uterine cervical carcinoma

A Mostowska, M Myka, M Lianeri, A Roszak… - Clinical …, 2011 - Elsevier
OBJECTIVE: It has been reported that aberrant DNA methylation can be associated with
HPV infection and cervical tumorigenesis. The aim of this study was to evaluate the …

Inhibition of DNA methyltransferase induces G2 cell cycle arrest and apoptosis in human colorectal cancer cells via inhibition of JAK2/STAT3/STAT5 signalling

H Xiong, ZF Chen, QC Liang, W Du… - Journal of cellular …, 2009 - Wiley Online Library
DNA methyltransferase inhibitors (MTIs) have recently emerged as promising
chemotherapeutic or preventive agents for cancer, despite their poorly characterized …