Type 2 immunity in the skin and lungs
CA Akdis, PD Arkwright, MC Brüggen, W Busse… - Allergy, 2020 - Wiley Online Library
There has been extensive progress in understanding the cellular and molecular
mechanisms of inflammation and immune regulation in allergic diseases of the skin and …
mechanisms of inflammation and immune regulation in allergic diseases of the skin and …
Mast cells as sources of cytokines, chemokines, and growth factors
Mast cells are hematopoietic cells that reside in virtually all vascularized tissues and that
represent potential sources of a wide variety of biologically active secreted products …
represent potential sources of a wide variety of biologically active secreted products …
[HTML][HTML] Neuroimmune communication regulating pruritus in atopic dermatitis
Atopic dermatitis (AD) is a common, chronic-relapsing inflammatory skin disease with
significant disease burden. Genetic and environmental trigger factors contribute to AD …
significant disease burden. Genetic and environmental trigger factors contribute to AD …
Proteolytic processing of interleukin-1 family cytokines: variations on a common theme
IS Afonina, C Müller, SJ Martin, R Beyaert - Immunity, 2015 - cell.com
Members of the extended interleukin-1 (IL-1) cytokine family, such as IL-1, IL-18, IL-33, and
IL-36, play a pivotal role in the initiation and amplification of immune responses. However …
IL-36, play a pivotal role in the initiation and amplification of immune responses. However …
IL-33 is processed into mature bioactive forms by neutrophil elastase and cathepsin G
E Lefrançais, S Roga, V Gautier… - Proceedings of the …, 2012 - National Acad Sciences
Interleukin-33 (IL-33)(NF-HEV) is a chromatin-associated nuclear cytokine from the IL-1
family, which has been linked to important diseases, including asthma, rheumatoid arthritis …
family, which has been linked to important diseases, including asthma, rheumatoid arthritis …
Endogenous IL-33 is highly expressed in mouse epithelial barrier tissues, lymphoid organs, brain, embryos, and inflamed tissues: in situ analysis using a novel Il-33 …
M Pichery, E Mirey, P Mercier, E Lefrancais… - The Journal of …, 2012 - journals.aai.org
IL-33 (previously known as NF from high endothelial venules) is an IL-1 family cytokine that
signals through the ST2 receptor and drives cytokine production in mast cells, basophils …
signals through the ST2 receptor and drives cytokine production in mast cells, basophils …
The dual function cytokine IL-33 interacts with the transcription factor NF-κB to dampen NF-κB–stimulated gene transcription
S Ali, A Mohs, M Thomas, J Klare, R Ross… - The Journal of …, 2011 - journals.aai.org
Full-length IL-33 is a member of the IL-1 family of cytokines, which can act in an autocrine or
paracrine manner by binding to the IL-33R on several different target cell types. In addition …
paracrine manner by binding to the IL-33R on several different target cell types. In addition …
The role of IL-1 family of cytokines and receptors in pathogenesis of COVID-19
S Makaremi, A Asgarzadeh, H Kianfar… - Inflammation …, 2022 - Springer
A global pandemic has erupted as a result of the new brand coronavirus, severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). This pandemic has been consociated …
respiratory syndrome coronavirus 2 (SARS-CoV-2). This pandemic has been consociated …
[HTML][HTML] Innate lymphoid cells in allergic and nonallergic inflammation
In the last decade, the full picture of the role of innate lymphoid cells (ILCs) has been
gradually revealed. ILCs are classified into 3 groups based on their transcription factors and …
gradually revealed. ILCs are classified into 3 groups based on their transcription factors and …
IL-33 is an unconventional Alarmin that stimulates IL-2 secretion by dendritic cells to selectively expand IL-33R/ST2+ regulatory T cells
BM Matta, JM Lott, LR Mathews, Q Liu… - The Journal of …, 2014 - journals.aai.org
IL-33 is a recently characterized IL-1 family member that is proposed to function as an
alarmin, or endogenous signal of cellular damage, as well as act as a pleiotropic cytokine …
alarmin, or endogenous signal of cellular damage, as well as act as a pleiotropic cytokine …