Developmental origins of metabolic diseases
Almost 2 billion adults in the world are overweight, and more than half of them are classified
as obese, while nearly one-third of children globally experience poor growth and …
as obese, while nearly one-third of children globally experience poor growth and …
Molecular biology of spermatogenesis: novel targets of apparently idiopathic male infertility
R Cannarella, RA Condorelli, LM Mongioì… - International journal of …, 2020 - mdpi.com
Male infertility affects half of infertile couples and, currently, a relevant percentage of cases
of male infertility is considered as idiopathic. Although the male contribution to human …
of male infertility is considered as idiopathic. Although the male contribution to human …
[HTML][HTML] Fetal manipulation of maternal metabolism is a critical function of the imprinted Igf2 gene
Maternal-offspring interactions in mammals involve both cooperation and conflict. The fetus
has evolved ways to manipulate maternal physiology to enhance placental nutrient transfer …
has evolved ways to manipulate maternal physiology to enhance placental nutrient transfer …
Maternal obesity and risk of low birth weight, fetal growth restriction, and macrosomia: multiple analyses
M Lewandowska - Nutrients, 2021 - mdpi.com
The associations between maternal pre-pregnancy obesity and low birth weight (LBW,<
2500 g) remain inconclusive. Therefore, birth weight in a Polish prospective cohort of 912 …
2500 g) remain inconclusive. Therefore, birth weight in a Polish prospective cohort of 912 …
Genomic map of candidate human imprint control regions: the imprintome
Imprinted genes–critical for growth, metabolism, and neuronal function–are expressed from
one parental allele. Parent-of-origin-dependent CpG methylation regulates this expression …
one parental allele. Parent-of-origin-dependent CpG methylation regulates this expression …
Regulation of maternal–fetal metabolic communication
CE Bowman, Z Arany, MJ Wolfgang - Cellular and molecular life sciences, 2021 - Springer
Pregnancy may be the most nutritionally sensitive stage in the life cycle, and improved
metabolic health during gestation and early postnatal life can reduce the risk of chronic …
metabolic health during gestation and early postnatal life can reduce the risk of chronic …
Epigenetics of pregnancy: looking beyond the DNA code
D Zuccarello, U Sorrentino, V Brasson, L Marin… - Journal of assisted …, 2022 - Springer
Epigenetics is the branch of genetics that studies the different mechanisms that influence
gene expression without direct modification of the DNA sequence. An ever-increasing …
gene expression without direct modification of the DNA sequence. An ever-increasing …
Distinction between the effects of parental and fetal genomes on fetal growth
T Juliusdottir, V Steinthorsdottir, L Stefansdottir… - Nature Genetics, 2021 - nature.com
Birth weight is a common measure of fetal growth that is associated with a range of health
outcomes. It is directly affected by the fetal genome and indirectly by the maternal genome …
outcomes. It is directly affected by the fetal genome and indirectly by the maternal genome …
Gender specific differences in disease susceptibility: the role of epigenetics
L Migliore, V Nicoli, A Stoccoro - Biomedicines, 2021 - mdpi.com
Many complex traits or diseases, such as infectious and autoimmune diseases, cancer,
xenobiotics exposure, neurodevelopmental and neurodegenerative diseases, as well as the …
xenobiotics exposure, neurodevelopmental and neurodegenerative diseases, as well as the …
Osteoarthritis and toll-like receptors: when innate immunity meets chondrocyte apoptosis
G Barreto, M Manninen, K K. Eklund - Biology, 2020 - mdpi.com
Osteoarthritis (OA) has long been viewed as a degenerative disease of cartilage, but
accumulating evidence indicates that inflammation has a critical role in its pathogenesis. In …
accumulating evidence indicates that inflammation has a critical role in its pathogenesis. In …