The role of microneedle arrays in drug delivery and patient monitoring to prevent diabetes induced fibrosis
E McAlister, M Kirkby, J Dominguez-Robles… - Advanced Drug Delivery …, 2021 - Elsevier
Diabetes affects approximately 450 million adults globally. If not effectively managed,
chronic hyperglycaemia causes tissue damage that can develop into fibrosis. Fibrosis leads …
chronic hyperglycaemia causes tissue damage that can develop into fibrosis. Fibrosis leads …
[HTML][HTML] Use of poly lactic-co-glycolic acid nano and micro particles in the delivery of drugs modulating different phases of inflammation
C Puricelli, CL Gigliotti, I Stoppa, S Sacchetti… - Pharmaceutics, 2023 - mdpi.com
Chronic inflammation contributes to the pathogenesis of many diseases, including
apparently unrelated conditions such as metabolic disorders, cardiovascular diseases …
apparently unrelated conditions such as metabolic disorders, cardiovascular diseases …
[HTML][HTML] Ginger alleviates hyperglycemia-induced oxidative stress, inflammation and apoptosis and protects rats against diabetic nephropathy
AM Al Hroob, MH Abukhalil, RD Alghonmeen… - Biomedicine & …, 2018 - Elsevier
Oxidative stress plays a major role in the development and progression of diabetic
nephropathy (DN). In this study, the potential protective effect of ginger (Zingiber officinale) …
nephropathy (DN). In this study, the potential protective effect of ginger (Zingiber officinale) …
Protective effect of vanillic acid against diabetes and diabetic nephropathy by attenuating oxidative stress and upregulation of NF‐κB, TNF‐α and COX‐2 proteins in …
Diabetes is the most prevalent disorder in the world characterized by uncontrolled high
blood glucose levels and nephropathy is one of the chief complications allied with …
blood glucose levels and nephropathy is one of the chief complications allied with …
Telmisartan attenuates diabetic nephropathy by mitigating oxidative stress and inflammation, and upregulating Nrf2/HO-1 signaling in diabetic rats
Diabetic nephropathy (DN) is a serious complication of diabetes and can lead to renal
failure. Telmisartan (TEL) is an approved angiotensin II type 1 receptor blocker for the …
failure. Telmisartan (TEL) is an approved angiotensin II type 1 receptor blocker for the …
Curcumin reverses diabetic nephropathy in streptozotocin-induced diabetes in rats by inhibition of PKCβ/p66Shc axis and activation of FOXO-3a
This study investigated if the nephroprotective effect of Curcumin in streptozotocin-induced
type 1 diabetes mellitus (DM) in rats involves downregulation/inhibition of p 66 Shc and …
type 1 diabetes mellitus (DM) in rats involves downregulation/inhibition of p 66 Shc and …
[HTML][HTML] Vascularized pulp regeneration via injecting simvastatin functionalized GelMA cryogel microspheres loaded with stem cells from human exfoliated deciduous …
X Yuan, Z Yuan, Y Wang, Z Wan, X Wang, S Yu… - Materials Today Bio, 2022 - Elsevier
Dental pulp necrosis are serious pathologic entities that causes tooth nutrition deficiency
and abnormal root development, while regeneration of functional pulp tissue is of paramount …
and abnormal root development, while regeneration of functional pulp tissue is of paramount …
[HTML][HTML] Notoginsenoside R1 Protects db/db Mice against Diabetic Nephropathy via Upregulation of Nrf2-Mediated HO-1 Expression
B Zhang, X Zhang, C Zhang, Q Shen, G Sun, X Sun - Molecules, 2019 - mdpi.com
Diabetic nephropathy (DN) is a leading cause of end-stage renal failure, and no effective
treatment is available. Notoginsenoside R1 (NGR1) is a novel saponin that is derived from …
treatment is available. Notoginsenoside R1 (NGR1) is a novel saponin that is derived from …
Glucose-responsive hydrogel enhances the preventive effect of insulin and liraglutide on diabetic nephropathy of rats
MQ Tong, LZ Luo, PP Xue, YH Han, LF Wang… - Acta Biomaterialia, 2021 - Elsevier
Diabetic nephropathy (DN) is one of the most serious complications of diabetes mellitus. The
combination of insulin (Ins) with liraglutide (Lir) has a greater potential for preventing DN …
combination of insulin (Ins) with liraglutide (Lir) has a greater potential for preventing DN …
[HTML][HTML] BM-MSCs alleviate diabetic nephropathy in male rats by regulating ER stress, oxidative stress, inflammation, and apoptotic pathways
T Khamis, A Abdelkhalek, H Abdellatif… - Frontiers in …, 2023 - frontiersin.org
Introduction: Diabetic nephropathy (DN), a chronic kidney disease, is a major cause of end-
stage kidney disease worldwide. Mesenchymal stem cells (MSCs) have become a …
stage kidney disease worldwide. Mesenchymal stem cells (MSCs) have become a …