Nanomedicine in treatment of breast cancer–A challenge to conventional therapy

M Afzal, KS Alharbi, NK Alruwaili, FA Al-Abassi… - Seminars in cancer …, 2021 - Elsevier
Amongst the various types of cancer, breast cancer is a highly heterogeneous disease and
known as the leading cause of death among women globally. The extensive interdisciplinary …

[PDF][PDF] Polymeric nanoparticles for breast cancer therapy: A comprehensive review

IK Grewal, S Singh, S Arora… - Biointerface Res. Appl …, 2021 - biointerfaceresearch.com
Breast cancer is a leading death cause in women globally. Since therapeutic products do
not yet approach the tumor tissue at adequate levels; therefore, nanoparticle-based …

[HTML][HTML] Quercetin synergistically enhances the anticancer efficacy of docetaxel through induction of apoptosis and modulation of PI3K/AKT, MAPK/ERK, and JAK …

A Safi, E Heidarian, R Ahmadi - International journal of molecular …, 2021 - ncbi.nlm.nih.gov
Docetaxel is widely used in the treatment of metastatic breast cancer. However, its
effectiveness is limited due to chemoresistance and its undesirable side effects. The …

Chitosan coated luteolin nanostructured lipid carriers: optimization, in vitro-ex vivo assessments and cytotoxicity study in breast cancer cells

SJ Gilani, M Bin-Jumah, M Rizwanullah, SS Imam… - Coatings, 2021 - mdpi.com
In the present study, luteolin (LTN)-encapsulated chitosan (CS) coated nanostructured lipid
carriers (NLCs) were formulated using the melt emulsification ultrasonication technique …

From oncogenic signaling pathways to single-cell sequencing of immune cells: changing the landscape of cancer immunotherapy

A Derakhshani, Z Rostami, H Safarpour, MA Shadbad… - Molecules, 2021 - mdpi.com
Over the past decade, there have been remarkable advances in understanding the signaling
pathways involved in cancer development. It is well-established that cancer is caused by the …

Molecular epigenetic dynamics in breast carcinogenesis

A Hazra, P Bose, P Sunita, SP Pattanayak - Archives of Pharmacal …, 2021 - Springer
Breast cancer has become one of the most common dreadful diseases that target women
across the globe. The most obvious reasons we associate with it are either genetic …

RNA interference: Promising approach for breast cancer diagnosis and treatment

E Allahyari, K Velaei, Z Sanaat… - Cell Biology …, 2023 - Wiley Online Library
Today, cancer is one of the main health‐related challenges, and in the meantime, breast
cancer (BC) is one of the most common cancers among women, with an alarming number of …

Nanoparticles for the Treatment of Bone Metastasis in Breast Cancer: Recent Advances and Challenges

X Yu, L Zhu - International Journal of Nanomedicine, 2024 - Taylor & Francis
Although the frequency of bone metastases from breast cancer has increased, effective
treatment is lacking, prompting the development of nanomedicine, which involves the use of …

Dual drug loaded nanostructured lipid carrier for cytotoxic effect against breast cancer-a drug repurposing approach

P Kumari, S Dang - Surfaces and Interfaces, 2023 - Elsevier
In the present study nanostructured lipid carrier with a combination of Metformin (MET) and
Thymoquinone (THY) was developed, characterized, and was further evaluated for cytotoxic …

Development and evaluation of luteolin loaded pegylated bilosome: optimization, in vitro characterization, and cytotoxicity study

A Zafar, NK Alruwaili, SS Imam, OA Alsaidan… - Drug Delivery, 2021 - Taylor & Francis
The present research was aimed to develop luteolin (LL) loaded pegylated bilosomes (PG-
BLs) for oral delivery. The luteolin bilosomes (BLs) were prepared by the thin-film hydration …