[HTML][HTML] Review of the efficacy of nanoparticle-based drug delivery systems for cancer treatment

K Elumalai, S Srinivasan, A Shanmugam - Biomedical Technology, 2024 - Elsevier
This review evaluates the literature on nanoparticle-based drug delivery systems for cancer
treatment and assesses their efficacy. Nanoparticles have shown potential for improving …

A panoramic perspective of recent progress in 2D and 3D covalent organic frameworks for drug delivery: Special Issue: Emerging Investigators

F Mehvari, V Ramezanzade, P Asadi, N Singh… - …, 2024 - Wiley Online Library
The development of efficient drug delivery systems is essential for improving the efficacy and
safety of cancer drugs, particularly for aggressive and difficult‐to‐treat cancers. Covalent …

[HTML][HTML] Unlocking the mitochondria for nanomedicine-based Treatments: Overcoming biological Barriers, improving Designs, and selecting verification techniques

C Pegoraro, I Domingo, I Conejos-Sánchez… - Advanced Drug Delivery …, 2024 - Elsevier
Enhanced targeting approaches will support the treatment of diseases associated with
dysfunctional mitochondria, which play critical roles in energy generation and cell survival …

Targeted co-delivery of FOXM1 aptamer and DOX by nucleolin aptamer-functionalized pH-responsive biocompatible nanodelivery system to enhance therapeutic …

M Masoudi, SM Taghdisi, G Hashemitabar… - Drug Delivery and …, 2024 - Springer
Targeted nanodelivery systems offer a promising approach to cancer treatment, including
the most common cancer in women, breast cancer. In this study, a targeted, pH-responsive …

Evolution of Pyrrolysyl-tRNA Synthetase: From Methanogenesis to Genetic Code Expansion

NG Koch, N Budisa - Chemical Reviews, 2024 - ACS Publications
Over 20 years ago, the pyrrolysine encoding translation system was discovered in specific
archaea. Our Review provides an overview of how the once obscure pyrrolysyl-tRNA …

[HTML][HTML] Design and synthesis of nucleotidyl lipids and their application in the targeted delivery of siG12D for pancreatic cancer therapy

Y Pan, Y Zhu, Y Ma, J Hong, W Zhao, Y Gao… - Biomedicine & …, 2024 - Elsevier
Nucleic acid drugs are attracting significant attention as prospective therapeutics. However,
their efficacy is hindered by challenges in penetrating cell membranes and reaching target …

[HTML][HTML] Regulatory Insights into Nanomedicine and Gene Vaccine Innovation: Safety Assessment, Challenges, and Regulatory Perspectives

EB Souto, C Blanco-Llamero, K Krambeck, NS Kiran… - Acta Biomaterialia, 2024 - Elsevier
This analysis explores the principal regulatory concerns linked to nanomedicines and gene
vaccines, including the complexities involved and the perspectives on how to navigate them …

PGC1α‐Inducing Senomorphic Nanotherapeutics Functionalized with NKG2D‐Overexpressing Cell Membranes for Intervertebral Disc Degeneration

S Liu, K Li, Y He, S Chen, W Yang, X Chen… - Advanced …, 2024 - Wiley Online Library
Cellular senescence is a significant contributor to intervertebral disc aging and
degeneration. However, the application of senotherapies, such as senomorphics targeting …

Advancing Cancer Therapy: Unveiling the Cutting-Edge Potential of Carmustine Nano Carriers for Targeted Treatment

A Khanizadeh, A Ghaemi, M Pourmadadi… - Journal of Drug Delivery …, 2024 - Elsevier
The use of nanoparticles (NPs) as drug delivery vehicles in cancer therapy has received
considerable attention in recent years. This review explores the novel use of carmustine …

Leveraging artificial intelligence in vaccine development: A narrative review

DB Olawade, J Teke, O Fapohunda… - Journal of …, 2024 - Elsevier
Vaccine development stands as a cornerstone of public health efforts, pivotal in curbing
infectious diseases and reducing global morbidity and mortality. However, traditional …