Importance Colorectal cancer (CRC) remains a significant cause of morbidity and mortality
in the United States. Objective To systematically review the effectiveness, diagnostic …

Importance Colorectal cancer (CRC) remains a significant cause of morbidity and mortality
in the US. Objective To systematically review the effectiveness, test accuracy, and harms of …

In the United States, colorectal cancer (CRC) is the third most common cancer diagnosed
among men and women and the second leading cause of death from cancer. CRC largely …

It is important that the medical professions play a significant role in critically evaluating the
use of diagnostic procedures and therapies in the detection, management, and prevention of …

Background We evaluated the performance characteristics of computed tomographic (CT)
virtual colonoscopy for the detection of colorectal neoplasia in an average-risk screening …

As multidetector CT has come to play a more central role in medical care and as CT image
quality has improved, there has been an increase in the frequency of detecting “incidental …

Background Computed tomographic (CT) colonography is a noninvasive option in screening
for colorectal cancer. However, its accuracy as a screening tool in asymptomatic adults has …

Background: In 2002, the US Preventive Services Task Force (USPSTF) recommended
colorectal cancer screening for adults 50 years of age or older but concluded that evidence …

Researchers, institutional review boards (IRBs), participants in human subjects research,
and their families face an important but largely neglected problem—how should incidental …

A 65-year-old man with a history of well-controlled hypertension presents for a follow-up visit
after an incidental finding of a small mass in the right kidney on an abdominal computed …