The protective association between the human leukocyte antigen HLA-B53 and severe
malaria was investigated by sequencing of peptides eluted from this molecule followed by …

Multilocus genotyping of microbial pathogens has revealed a range of population structures,
with some bacteria showing extensive recombination and others showing almost complete …

Host-parasite coevolution has been likened to a molecular arms race, with particular
parasite genes evolving to evade specific host defenses. Study of the variants of an …

There are four species of human malarial parasite and several monkey ones, and in
evolutionary terms the human and non-human primate plasmodia may be related. The tools …

RTS, S is the most advanced malaria vaccine candidate, currently under phase-III clinical
trials in Africa. This Plasmodium falciparum vaccine contains part of the central repeat region …

The present data provide the first evidence that a protozoan parasite, Plasmodium
falciparum, can induce CD4+ cytotoxic T cells in man. The CD4+ cytotoxic T lymphocytes …

The development of an effective malaria vaccine is a feasible goal. Most of the vaccines
being developed today are subunit vaccines derived from selected parasite antigens or their …

We have investigated the genetic diversity of the gene encoding the CS protein. A total of 75
complete and 96 partial sequences are studied. We find high levels of genetic …

Genetic variation of the glutamate-rich protein (GLURP) of Plasmodium falciparum was
analysed in 29 field isolates and 15 laboratory lines of diverse geographical origin, by DNA …

A Plasmodium vivax-like human malaria parasite was recently identified from Madang, a
holoendemic malarious region in Papua New Guinea. The complete nucleotide sequence of …