RNA has diverse cellular functionality, including regulating gene expression, protein
translation, and cellular response to stimuli, due to its intricate structures. Over the past …

With the advancement of sequencing technologies and bioinformatics, over than 170
different RNA modifications have been identified. However, only a few of these modifications …

Adenosine deaminases acting on RNA (ADARs) are endogenous enzymes catalyzing the
deamination of adenosines to inosines, which are then read as guanosines during …

Recruiting the endogenous editing enzyme adenosine deaminase acting on RNA (ADAR)
with tailored guide RNAs for adenosine-to-inosine (A-to-I) RNA base editing is promising for …

Epitranscriptomics is a field that delves into post-transcriptional changes. Among these
modifications, the conversion of adenosine to inosine, traduced as guanosine (A> I (G)), is …

Inosine (I), resulting from the deamination of adenosine (A), is a prominent modification in
the human transcriptome. The enzymes responsible for the conversion of adenosine to …

In this article, I recount my memories of key experiments that led to my entry into the RNA
editing/modification field. I highlight initial observations made by the pioneers in the ADAR …

Synthetic DNA-protein conjugates have found widespread applications in diagnostics and
therapeutics, prompting a growing interest in developing chemical biology methodologies …

Abstract Astrocyte elevated gene-1 (AEG-1) oncogene is a notorious and evolving target in a
variety of human malignancies including osteosarcoma. The RNA interference (RNAi) has …

ADAR (Adenosine Deaminases Acting on RNA) proteins are a group of enzymes that play a
vital role in RNA editing by converting adenosine to inosine in RNAs. This process is a …