Matrix-binding isoforms and non-matrix-binding isoforms of vascular endothelial growth
factor (VEGF) are both capable of stimulating vascular remodeling, but the resulting blood …

Angiogenesis (neovascularization) plays a crucial role in a variety of physiological and
pathological conditions including cancer, cardiovascular disease, and wound healing …

Vascular endothelial growth factor (VEGF), through its activation of cell surface receptor
tyrosine kinases including VEGFR1 and VEGFR2, is a vital regulator of stimulatory and …

Abstract Vascular Endothelial Growth Factor Receptor-2 (VEGFR2) is a pro-angiogenic
receptor, expressed on endothelial cells (ECs). Although biochemical pathways that follow …

Distribution of vascular endothelial cell growth factor A (VEGF-A) as a gradient determines
microvascular endothelial cell (EC) fate during organogenesis. While much is understood …

The endothelial nitric oxide synthase (eNOS) signaling pathway in endothelial cells has
multiple physiological significances. It produces nitric oxide (NO), an important vasodilator …

Vascular endothelial growth factor (VEGF) is a potent cytokine that binds to specific
receptors on the endothelial cells lining blood vessels. The signaling cascade triggered …

Vascular endothelial growth factor (VEGF) is a key regulator of angiogenesis–the growth of
new microvessels from existing microvasculature. Angiogenesis is a complex process …

Abstract Vascular Endothelial Growth Factor (VEGF) signal transduction is central to
angiogenesis in development and in pathological conditions such as cancer, retinopathy …

VEGF is a key promoter of angiogenesis and a major target of proangiogenic therapy for
peripheral arterial disease (PAD). Greater understanding of VEGF angiogenic signaling and …