Endothelial cells (ECs) exhibit dramatic plasticity of form at the single-and collective-cell
level during new vessel growth, adult vascular homeostasis, and pathology. Understanding …

The vascular network carries blood throughout the body, delivering oxygen to tissues and
providing a pathway for communication between distant organs. The network is hierarchical …

Recent findings indicate that VEGF receptors and coreceptors (neuropilins; NRP) are
expressed on nonendothelial cells in human bladder urothelium, in one human bladder …

Tumor growth and progression are critically dependent on the establishment of a vascular
support system. This is often accomplished via the expression of pro-angiogenic growth …

We simulate the dynamics of a growing, vascular tumor with a heterogeneous vasculature
and its behaviour under combination chemotherapy. The studied model includes two spatial …

Cells interact with the extracellular environment by means of receptor molecules on their
surface. Receptors can bind different ligands, leading to the formation of receptor–ligand …

One of the relatively new modalities in treatment of cancer is antiangiogenic therapy (AAT),
which stops the formation of new blood vessels, thus leading to nutrient deprivation of a …

Antiangiogenic therapy (AAT) is an indirect oncological modality that is aimed at the
disruption of cancer cell nutrient supply. Invasive tumors have been shown to possess …

To investigate (1) the effect of vascular endothelial growth factor B (VEGFB) on lipid
accumulation and the alteration of fatty acids and fatty acid-related enzymes in C2C12 …

The biology of cancer is a complex interplay of many underlying processes, taking place at
different scales both in space and time. A variety of theoretical models have been …