[HTML][HTML] Scientific rationale for developing potent RBD-based vaccines targeting COVID-19
H Kleanthous, JM Silverman, KW Makar, IK Yoon… - npj Vaccines, 2021 - nature.com
Vaccination of the global population against COVID-19 is a great scientific, logistical, and
moral challenge. Despite the rapid development and authorization of several full-length …
moral challenge. Despite the rapid development and authorization of several full-length …
Advances in SARS-CoV-2 receptor-binding domain-based COVID-19 vaccines
ABSTRACT Introduction The Coronavirus Disease 2019 (COVID-19) pandemic has caused
devastating human and economic costs. Vaccination is an important step in controlling the …
devastating human and economic costs. Vaccination is an important step in controlling the …
SARS-CoV-2 receptor binding domain displayed on HBsAg virus–like particles elicits protective immunity in macaques
NC Dalvie, LH Tostanoski, SA Rodriguez-Aponte… - Science …, 2022 - science.org
Authorized vaccines against SARS-CoV-2 remain less available in low-and middle-income
countries due to insufficient supply, high costs, and storage requirements. Global immunity …
countries due to insufficient supply, high costs, and storage requirements. Global immunity …
[HTML][HTML] An engineered SARS-CoV-2 receptor-binding domain produced in Pichia pastoris as a candidate vaccine antigen
M Limonta-Fernández, G Chinea-Santiago… - New …, 2022 - Elsevier
Developing affordable and easily manufactured SARS-CoV-2 vaccines will be essential to
achieve worldwide vaccine coverage and long-term control of the COVID-19 pandemic …
achieve worldwide vaccine coverage and long-term control of the COVID-19 pandemic …
[HTML][HTML] Enabling growth-decoupled Komagataella phaffii recombinant protein production based on the methanol-free PDH promoter
N Bernat-Camps, K Ebner, V Schusterbauer… - … in Bioengineering and …, 2023 - frontiersin.org
The current transition towards the circular bioeconomy requires a rational development of
biorefineries to sustainably fulfill the present demands. The use of Komagataella phaffii …
biorefineries to sustainably fulfill the present demands. The use of Komagataella phaffii …
RBD-VLP vaccines adjuvanted with Alum or SWE protect K18-hACE2 mice against SARS-CoV-2 VOC challenge
The ongoing COVID-19 pandemic has contributed largely to the global vaccine disparity.
Development of protein subunit vaccines can help alleviate shortages of COVID-19 vaccines …
Development of protein subunit vaccines can help alleviate shortages of COVID-19 vaccines …
[HTML][HTML] Carbohydrate fatty acid monosulphate: oil-in-water adjuvant enhances SARS-CoV-2 RBD nanoparticle-induced immunogenicity and protection in mice
Abstract Development of SARS-CoV-2 vaccines that protect vulnerable populations is a
public health priority. Here, we took a systematic and iterative approach by testing several …
public health priority. Here, we took a systematic and iterative approach by testing several …
Identification of a novel growth-associated promoter for biphasic expression of heterogenous proteins in Pichia pastoris
Q Shen, J Cui, Y Wang, ZC Hu, YP Xue… - Applied and …, 2024 - Am Soc Microbiol
Pichia pastoris (P. pastoris) is one of the most popular cell factories for expressing
exogenous proteins and producing useful chemicals. The alcohol oxidase 1 promoter …
exogenous proteins and producing useful chemicals. The alcohol oxidase 1 promoter …
Antigen-adjuvant interactions, stability, and immunogenicity profiles of a SARS-CoV-2 receptor-binding domain (RBD) antigen formulated with aluminum salt and CpG …
Low-cost, refrigerator-stable COVID-19 vaccines will facilitate global access and improve
vaccine coverage in low-and middle-income countries. To this end, subunit-based …
vaccine coverage in low-and middle-income countries. To this end, subunit-based …
From Lab to Table: the path of recombinant milk proteins in transforming dairy production.
IN Piazenski, JPM Candelário, VT Soccol… - Trends in Food Science …, 2024 - Elsevier
Background Recombinant milk protein production is emerging as a pivotal innovation in the
dairy industry, driven by the need for sustainable and ethically produced dairy alternatives …
dairy industry, driven by the need for sustainable and ethically produced dairy alternatives …