Recent strategies to develop innovative photosensitizers for enhanced photodynamic therapy
TC Pham, VN Nguyen, Y Choi, S Lee, J Yoon - Chemical Reviews, 2021 - ACS Publications
This review presents a robust strategy to design photosensitizers (PSs) for various species.
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …
Synergistic antibacterial strategy based on photodynamic therapy: Progress and perspectives
X Hu, H Zhang, Y Wang, BC Shiu, JH Lin… - Chemical Engineering …, 2022 - Elsevier
The dramatic increase in drug resistant bacteria resistance to existing conventional
antibiotics poses a great challenge to the effective treatment of infectious diseases …
antibiotics poses a great challenge to the effective treatment of infectious diseases …
Clinical development of metal complexes as photosensitizers for photodynamic therapy of cancer
J Karges - Angewandte Chemie International Edition, 2022 - Wiley Online Library
Cancer has emerged over the last decades as one of the deadliest diseases in the world.
Among the most commonly used techniques (ie surgery, immunotherapy, radiotherapy or …
Among the most commonly used techniques (ie surgery, immunotherapy, radiotherapy or …
Near-infrared metal agents assisting precision medicine: from strategic design to bioimaging and therapeutic applications
C Li, Y Pang, Y Xu, M Lu, L Tu, Q Li… - Chemical Society …, 2023 - pubs.rsc.org
Metal agents have made incredible strides in preclinical research and clinical applications in
recent years, but their short emission/absorption wavelengths continue to be a barrier to …
recent years, but their short emission/absorption wavelengths continue to be a barrier to …
Heavy-atom-free photosensitizers: from molecular design to applications in the photodynamic therapy of cancer
VN Nguyen, Y Yan, J Zhao, J Yoon - Accounts of chemical …, 2020 - ACS Publications
Conspectus Photodynamic therapy (PDT) is a clinically approved therapeutic modality that
has shown great potential for the treatment of cancers owing to its excellent spatiotemporal …
has shown great potential for the treatment of cancers owing to its excellent spatiotemporal …
Luminescent first-row transition metal complexes
C Wegeberg, OS Wenger - Jacs Au, 2021 - ACS Publications
Precious and rare elements have traditionally dominated inorganic photophysics and
photochemistry, but now we are witnessing a paradigm shift toward cheaper and more …
photochemistry, but now we are witnessing a paradigm shift toward cheaper and more …
Photodecaging of a mitochondria-localized iridium (III) endoperoxide complex for two-photon photoactivated therapy under hypoxia
Despite the clinical success of photodynamic therapy (PDT), the application of this medical
technique is intrinsically limited by the low oxygen concentrations found in cancer tumors …
technique is intrinsically limited by the low oxygen concentrations found in cancer tumors …
Near-infrared-activated anticancer platinum (IV) complexes directly photooxidize biomolecules in an oxygen-independent manner
Conventional light-driven cancer therapeutics require oxygen and visible light to indirectly
damage biomolecules, limiting their efficacy in deep, hypoxic tumours. Here we report the …
damage biomolecules, limiting their efficacy in deep, hypoxic tumours. Here we report the …
Long wavelength–emissive Ru (II) metallacycle–based photosensitizer assisting in vivo bacterial diagnosis and antibacterial treatment
Y Xu, C Li, X Ma, W Tuo, L Tu, X Li… - Proceedings of the …, 2022 - National Acad Sciences
Ruthenium (Ru) complexes are developed as latent emissive photosensitizers for cancer
and pathogen photodiagnosis and therapy. Nevertheless, most existing Ru complexes are …
and pathogen photodiagnosis and therapy. Nevertheless, most existing Ru complexes are …
Photosensitizers for photodynamic therapy
M Lan, S Zhao, W Liu, CS Lee… - Advanced healthcare …, 2019 - Wiley Online Library
As an emerging clinical modality for cancer treatment, photodynamic therapy (PDT) takes
advantage of the cytotoxic activity of reactive oxygen species (ROS) that are generated by …
advantage of the cytotoxic activity of reactive oxygen species (ROS) that are generated by …