Nerine Herbert, family Amaryllidaceae, is a genus of about 30 species that are native to
South Africa, Botswana, Lesotho, Namibia, and Swatini (formerly known as Swaziland) …

Aim: A breakthrough in modern medicine, in terms of treatment of Alzheimer's disease, is yet
to be seen, as the scene is currently plagued with numerous clinical trial failures. Here, we …

Tremendous efforts have been dedicated to the development of effective therapeutics
against Alzheimer's disease, which represents the most common debilitating …

Alzheimer's disease is a neurodegenerative disorder that impacts memory, thinking, and
behavior, and currently, there is no effective cure available for its treatment. This study …

Multifunctional ligands as an essential variant of polypharmacology are promising
candidates for the treatment of multi-factorial diseases like Alzheimer's disease. Based on …

This study aimed to investigate the phytochemical compositions and biological activities of
the Thymus cariensis and T. cilicicus. The phytochemical compositions were identified by …

ABSTRACT Introduction: Butyrylcholinesterase (BuChE) has obtained a renewed interest as
therapeutic target in Alzheimer's disease (AD), when changes in BuChE activity and …

A novel family of donepezil–ferulic acid hybrids were designed, synthesized and biologically
evaluated as multi-target-directed ligands against Alzheimer's disease by fusing a fragment …

In this study, the antioxidant, carbohydrate metabolism, cholinergic, monoaminergic, and
purinergic enzyme activities of ethyl acetate leaf fraction of Cnidoscolus aconitifolius were …

In recent studies, several alkaloids acting as cholinesterase inhibitors were isolated from
Corydalis cava (Papaveraceae). Inhibitory activities of (+)-thalictricavine (1) and (+) …