The opioids hold a unique place amongst addictive substances in that they have a critical
and indispensable role in medical treatment. This is as true today as it was in ancient times …

To obtain the durable benefits of opioid analgesia, physicians must develop strategies to
manage the negative attributes of opioid therapy. Side effects, opioid tolerance, and toxicity …

Pain is defined by the International Association for the Study of Pain as “an unpleasant
sensory and emotional experience associated with actual or potential tissue damage, or …

Die Behandlung von Tumorschmerzen, insbesondere neuropathischen Ursprungs, stellt in
vielen Fällen eine therapeutische Herausforderung dar. Nach den WHO-Empfehlungen sind …

A commentary on the problem of tolerance to opioids is presented from the perspective of a
person with chronic nonmalignant pain. The writer challenges the position of many clinicians …

Los antinflamatorios no esteroideos (AINE) y los opioides son los dos grandes grupos
analgésicos indicados para tratar el dolor agudo moderado-intenso; con una eficacia …

Effective relief of chronic intense pain is still a serious problem. The article analyzes the
main changes in the federal regulatory and legal framework that expand the rights of …

In many clinical situations, there is no medication that controls pain better than an opioid. Its
effects are immediate, based in key areas of the central nervous system that process pain …

Cílem této bakalářské práce bylo shromáždit poznatky týkající se klinického významu
opioidních léčiv, konkrétně morfinu a methadonu, a jejich mechanismu působení …

There is increasing evidence that in some patients, opioids can relieve chronic noncancer
pain (CNCP). However, the evidence is limited to relatively short-term studies which …