Stress granules (SGs) are membraneless cell compartments formed in response to different
stress stimuli, wherein translation factors, mRNAs, RNA-binding proteins (RBPs) and other …

Cancer‐related gene expression programs are strongly influenced by posttranscriptional
mechanisms. The RNA‐binding protein HuR is highly abundant in many cancers. Numerous …

Little information is available about how post-transcriptional mechanisms regulate the aging
process. Here, we show that the RNA-binding protein Pumilio2 (PUM2), which is a …

SIRT1 is increasingly recognized as a critical regulator of stress responses, replicative
senescence, inflammation, metabolism, and aging. SIRT1 expression is regulated …

The eukaryotic stress response involves translational suppression of non-housekeeping
proteins and the sequestration of unnecessary mRNA transcripts into stress granules (SGs) …

Aging represents the major risk factor for the onset and/or progression of various disorders
including neurodegenerative diseases, metabolic disorders, and bone-related defects. As …

Messenger RNA decay is a critical mechanism to control the expression of many
inflammation-and cancer-associated genes. These transcripts are targeted for rapid …

Adenylate‐and uridylate‐rich element (ARE) motifs are cis‐acting elements present in the
3′ untranslated region of mRNA transcripts that encode many inflammation‐and cancer …

Cellular senescence is a complex biological process that leads to irreversible cell‐cycle
arrest. Various extrinsic and intrinsic insults are associated with the onset of cellular …

Gene expression patterns in cancer cells are strongly influenced by posttranscriptional
mechanisms. RNA‐binding proteins (RBPs) play key roles in posttranscriptional gene …