Recent advances in hyperthermia therapy‐based synergistic immunotherapy

M Chang, Z Hou, M Wang, C Li, J Lin - Advanced Materials, 2021 - Wiley Online Library
The past decades have witnessed hyperthermia therapy (HTT) as an emerging strategy
against malignant tumors. Nanomaterial‐based photothermal therapy (PTT) and magnetic …

[PDF][PDF] Novel approaches for vaccine development

MS Gebre, LA Brito, LH Tostanoski, DK Edwards… - Cell, 2021 - cell.com
Vaccines are critical tools for maintaining global health. Traditional vaccine technologies
have been used across a wide range of bacterial and viral pathogens, yet there are a …

Advances in nanomaterial vaccine strategies to address infectious diseases impacting global health

CN Fries, EJ Curvino, JL Chen, SR Permar… - Nature …, 2021 - nature.com
Despite the overwhelming success of vaccines in preventing infectious diseases, there
remain numerous globally devastating diseases without fully protective vaccines, particularly …

[HTML][HTML] Design challenges in polymeric scaffolds for tissue engineering

MI Echeverria Molina, KG Malollari… - … in Bioengineering and …, 2021 - frontiersin.org
Numerous surgical procedures are daily performed worldwide to replace and repair
damaged tissue. Tissue engineering is the field devoted to the regeneration of damaged …

Application of Ti3C2 MXene Quantum Dots for Immunomodulation and Regenerative Medicine

A Rafieerad, W Yan, GL Sequiera… - Advanced …, 2019 - Wiley Online Library
Inflammation is tightly linked to tissue injury. In regenerative medicine, immune activation
plays a key role in rejection of transplanted stem cells and reduces the efficacy of stem cell …

Biocompatibility evolves: phenomenology to toxicology to regeneration

L Crawford, M Wyatt, J Bryers… - Advanced healthcare …, 2021 - Wiley Online Library
The word “biocompatibility,” is inconsistent with the observations of healing for so‐called
biocompatible biomaterials. The vast majority of the millions of medical implants in humans …

De novo design of functional zwitterionic biomimetic material for immunomodulation

B Li, Z Yuan, P Jain, HC Hung, Y He, X Lin… - Science …, 2020 - science.org
Superhydrophilic zwitterionic polymers are a class of nonfouling materials capable of
effectively resisting any nonspecific interactions with biological systems. We designed here …

Engineering the lymph node environment promotes antigen-specific efficacy in type 1 diabetes and islet transplantation

JM Gammon, ST Carey, V Saxena, HB Eppler… - Nature …, 2023 - nature.com
Antigen-specific tolerance is a key goal of experimental immunotherapies for autoimmune
disease and allograft rejection. This outcome could selectively inhibit detrimental …

[HTML][HTML] Development of ImmTOR tolerogenic nanoparticles for the mitigation of anti-drug antibodies

TK Kishimoto - Frontiers in Immunology, 2020 - frontiersin.org
The development of anti-drug antibodies (ADAs) is a common cause for treatment failure
and hypersensitivity reactions for many biologics. The focus of this review is the …

Cargo-less nanoparticles program innate immune cell responses to toll-like receptor activation

LM Casey, S Kakade, JT Decker, JA Rose, K Deans… - Biomaterials, 2019 - Elsevier
Developing biomaterials to control the responsiveness of innate immune cells represents a
clinically relevant approach to treat diseases with an underlying inflammatory basis, such as …