Tolerogenic Nano-/Microparticle Vaccines for Immunotherapy

Q Liu, G Chen, X Liu, L Tao, Y Fan, T Xia - ACS nano, 2024 - ACS Publications
Autoimmune diseases, allergies, transplant rejections, generation of antidrug antibodies,
and chronic inflammatory diseases have impacted a large group of people across the globe …

Nanoparticle internalization promotes the survival of primary macrophages

BM Jarai, CA Fromen - Advanced nanobiomed research, 2022 - Wiley Online Library
Macrophages, a class of tissue resident innate immune cells, are responsible for
sequestering foreign objects through the process of phagocytosis, making them a promising …

The impact of nanocarriers in the induction of antigen-specific immunotolerance in autoimmune diseases

F Dangkoub, M Sankian, M Tafaghodi… - Journal of Controlled …, 2021 - Elsevier
Immunotolerance induction in an antigen-specific manner is the long-term goal of
immunotherapy to treat autoimmune diseases. Nanocarriers (NCs) can be designed as a …

Autoantigen-specific immune tolerance in pathological and physiological cell death: Nanotechnology comes into view

A Tajbakhsh, N Farahani, SM Gheibihayat… - International …, 2021 - Elsevier
Apoptotic cells are tolerogenic and can present self-antigens in the absence of inflammation,
to antigen-presenting cells by the process of efferocytosis, resulting in anergy and depletion …

Harnessing Biomaterials to Study and Direct Antigen-Specific Immunotherapy

C Edwards, ST Carey, CM Jewell - ACS Applied Bio Materials, 2023 - ACS Publications
Immunotherapies are an evolving treatment paradigm for addressing cancer, autoimmunity,
and infection. While exciting, most of the existing therapies are limited by their specificity─ …

Electrospun poly (ε‐caprolactone)/poly (glycerol sebacate) aligned fibers fabricated with benign solvents for tendon tissue engineering

F Iorio, M El Khatib, N Wöltinger… - … Research Part A, 2024 - Wiley Online Library
The electrospinning technique is a commonly employed approach to fabricate fibers
intended for various tissue engineering applications. The aim of this study is to develop a …

Immunoengineering has arrived

JJ Green - Journal of Biomedical Materials Research Part A, 2021 - Wiley Online Library
Immunoengineering is a new discipline that creates and applies engineering tools and
principles to investigate and modulate the immune system. It spans from the molecular scale …

Natural Nano-Minerals (NNMs): Conception, Classification and Their Biomedical Composites

F Feng, Y Zhang, X Zhang, B Mu, W Qu, P Wang - ACS omega, 2024 - ACS Publications
Natural nano-minerals (NNMs) are minerals that are derived from nature with a size of less
than 100 nm in at least one dimension in size. NNMs have a number of excellent properties …

Unlocking Transplant Tolerance with Biomaterials

JPA Pham, MM Coronel - Advanced Healthcare Materials, 2024 - Wiley Online Library
For patients suffering from organ failure due to injury or autoimmune disease, allogeneic
organ transplantation with chronic immunosuppression is considered the gold standard in …

Tailoring biomaterials for vaccine delivery

Y Zhuo, H Zeng, C Su, Q Lv, T Cheng, L Lei - Journal of …, 2024 - Springer
Biomaterials are substances that can be injected, implanted, or applied to the surface of
tissues in biomedical applications and have the ability to interact with biological systems to …