Designing biomaterials for the treatment of autoimmune diseases
B Tang, X Xie, J Lu, W Huang, J Yang, J Tian… - Applied Materials …, 2024 - Elsevier
Autoimmune diseases (ADs) are a group of chronic relapsing inflammatory diseases that
cause great suffering to patients and increase the economic burden of society. However, the …
cause great suffering to patients and increase the economic burden of society. However, the …
Immunoengineering has arrived
JJ Green - Journal of Biomedical Materials Research Part A, 2021 - Wiley Online Library
Immunoengineering is a new discipline that creates and applies engineering tools and
principles to investigate and modulate the immune system. It spans from the molecular scale …
principles to investigate and modulate the immune system. It spans from the molecular scale …
New therapeutic approaches for allergy: A review of cell therapy and bio-or nano-material-based strategies
Allergy constitutes a major health issue due to its large prevalence. The established
therapeutic approaches (allergen avoidance, antihistamines, and corticosteroids) do not …
therapeutic approaches (allergen avoidance, antihistamines, and corticosteroids) do not …
ABCD of IA: A multi-scale agent-based model of T cell activation in inflammatory arthritis
DA McBride, JS Wang, WT Johnson, N Bottini… - Biomaterials …, 2024 - pubs.rsc.org
Biomaterial-based agents have been demonstrated to regulate the function of immune cells
in models of autoimmunity. However, the complexity of the kinetics of immune cell activation …
in models of autoimmunity. However, the complexity of the kinetics of immune cell activation …
Biomaterials for topical and transdermal drug delivery in reconstructive transplantation
Lifelong systemic immunosuppression remains the biggest challenge in vascularized
composite allotransplantation (VCA) due to the adverse effects it causes. Since VCA is a life …
composite allotransplantation (VCA) due to the adverse effects it causes. Since VCA is a life …
Targeting lymphoid tissues to promote immune tolerance
XY Chen, GS Du, X Sun - Advanced Therapeutics, 2021 - Wiley Online Library
The enormous research progress in autoimmune disorders makes the establishment of long‐
term clinical tolerance to autoantigens an accessible goal. This strategy endows lymphoid …
term clinical tolerance to autoantigens an accessible goal. This strategy endows lymphoid …
Engineering strategies for allogeneic solid tissue acceptance
Advances in allogeneic transplantation of solid organs and tissues depend on our
understanding of mechanisms that mediate the prevention of graft rejection. For the past …
understanding of mechanisms that mediate the prevention of graft rejection. For the past …
The Biocomplex Assembled from Antigen Peptide and Toll‐like Receptor Agonist Improved the Immunity against Pancreatic Adenocarcinoma In Vivo
W Feng, H Yu, T Xue, C Wu, F Ren… - Journal of Oncology, 2022 - Wiley Online Library
Purpose. One of the biggest challenges in cancer immunotherapy is generating robust
cancer‐specific immunity. This work describes using a biocomplex assembled from a toll …
cancer‐specific immunity. This work describes using a biocomplex assembled from a toll …
[PDF][PDF] Scaffold-mediated immunoengineering as innovative strategy for tendon regeneration. Cells. 2022; 11: 266
Tendon injuries are at the frontier of innovative approaches to public health concerns and
sectoral policy objectives. Indeed, these injuries remain difficult to manage due to tendon's …
sectoral policy objectives. Indeed, these injuries remain difficult to manage due to tendon's …
Biomaterials as tools for re-balancing skewed immunity in rheumatoid arthritis
P Zhang, H Jia - Translational Autoimmunity, 2023 - Elsevier
Rheumatoid arthritis (RA) is a systemic autoimmune disease featured by skewed immunity
that can cause joint inflammation and cartilage destruction. Existing clinical therapeutic …
that can cause joint inflammation and cartilage destruction. Existing clinical therapeutic …