Worldwide obesity is increasing at an alarming rate in children and adolescents, with the
consequent emergence of co-morbidities. Moreover, the maternal environment during …

Intrauterine growth restriction (IUGR) is strongly associated with obesity in adult life. The
mechanisms contributing to the onset of IUGR‐associated adult obesity have been studied …

In all mammals, white adipose tissue (WAT) and brown adipose tissue (BAT) are found
together in several fat depots, forming a multi-depot organ. Adrenergic stimulation induces …

Brown adipocytes (BA) generate heat in response to sympathetic activation and are the
main site of nonshivering thermogenesis in mammals. Although most BA are located in …

Inducing brown adipocytes in white adipose tissues is a promising target to combat obesity
and its related disorders in human beings. This goal has been especially encouraged by …

During the first month of postnatal life, adipose tissue depots of mice go through a drastic,
but transient, remodeling process. Between postnatal days 10 and 20, several white fat …

Maintenance of adipocyte precursors is critical for regulating metabolism and preventing
obesity related disease. These precursors have been immortalized and studied in cellular …

To determine the differences between brown adipocytes from interscapular brown tissue
(iBAT) and those induced in white adipose tissue (WAT) with respect to their thermogenic …

During postnatal development of mice distinct white adipose tissue depots display a
transient appearance of brown-like adipocytes. These brite (brown in white) adipocytes …

Recently, there has been great attention given to the possibility of combating obesity by
targeting brown fat activity or increasing differentiation of brown adipocytes in white fat …