Biological properties and clinical applications of berberine
D Song, J Hao, D Fan - Frontiers of Medicine, 2020 - Springer
Berberine, an isoquinoline alkaloid isolated from the Chinese herb Coptis chinensis and
other Berberis plants, has a wide range of pharmacological properties. Berberine can be …
other Berberis plants, has a wide range of pharmacological properties. Berberine can be …
AMPK as a therapeutic target for treating metabolic diseases
EA Day, RJ Ford, GR Steinberg - Trends in Endocrinology & Metabolism, 2017 - cell.com
The AMP-activated protein kinase (AMPK) is a central regulator of multiple metabolic
pathways and may have therapeutic importance for treating obesity, insulin resistance, type …
pathways and may have therapeutic importance for treating obesity, insulin resistance, type …
[HTML][HTML] Berberine in cardiovascular and metabolic diseases: from mechanisms to therapeutics
Cardiovascular and metabolic diseases (CVMD) are the leading causes of death worldwide,
underscoring the urgent necessity to develop new pharmacotherapies. Berberine (BBR) is …
underscoring the urgent necessity to develop new pharmacotherapies. Berberine (BBR) is …
[HTML][HTML] AMPK in skeletal muscle function and metabolism
R Kjøbsted, JR Hingst, J Fentz, M Foretz… - The FASEB …, 2018 - ncbi.nlm.nih.gov
Skeletal muscle possesses a remarkable ability to adapt to various physiologic conditions.
AMPK is a sensor of intracellular energy status that maintains energy stores by fine-tuning …
AMPK is a sensor of intracellular energy status that maintains energy stores by fine-tuning …
Antioxidant effects and mechanisms of medicinal plants and their bioactive compounds for the prevention and treatment of type 2 diabetes: an updated review
JO Unuofin, SL Lebelo - Oxidative medicine and cellular …, 2020 - Wiley Online Library
Diabetes mellitus is a metabolic disorder that majorly affects the endocrine gland, and it is
symbolized by hyperglycemia and glucose intolerance owing to deficient insulin secretory …
symbolized by hyperglycemia and glucose intolerance owing to deficient insulin secretory …
[HTML][HTML] Therapeutic effect of berberine on metabolic diseases: Both pharmacological data and clinical evidence
X Xu, H Yi, J Wu, T Kuang, J Zhang, Q Li, H Du… - Biomedicine & …, 2021 - Elsevier
The increased incidence of metabolic diseases (eg, diabetes and obesity) has seriously
affected human health and life safety worldwide. It is of great significance to find effective …
affected human health and life safety worldwide. It is of great significance to find effective …
Coptidis Rhizoma: a comprehensive review of its traditional uses, botany, phytochemistry, pharmacology and toxicology
J Wang, L Wang, GH Lou, HR Zeng, J Hu… - Pharmaceutical …, 2019 - Taylor & Francis
Abstract Context: Coptidis rhizome (CR), also known as Huanglian in Chinese, is the
rhizome of Coptis chinensis Franch., C. deltoidea CY Cheng et Hsiao, or C. teeta Wall …
rhizome of Coptis chinensis Franch., C. deltoidea CY Cheng et Hsiao, or C. teeta Wall …
Berberine as a natural modulator of inflammatory signaling pathways in the immune system: Focus on NF‐κB, JAK/STAT, and MAPK signaling pathways
SM Haftcheshmeh, M Abedi… - Phytotherapy …, 2022 - Wiley Online Library
Three main inflammatory signaling pathways include nuclear factor‐κB (NF‐κB), Janus
kinases/Signal transducer and activator of transcriptions (JAKs/STATs), and mitogen …
kinases/Signal transducer and activator of transcriptions (JAKs/STATs), and mitogen …
Berberis Vulgaris and Berberine: An Update Review
M Imenshahidi, H Hosseinzadeh - Phytotherapy research, 2016 - Wiley Online Library
Berberine is an isoquinoline alkaloid present in several plants, including Coptis sp. and
Berberis sp. Berberine is a customary component in Chinese medicine, and is characterized …
Berberis sp. Berberine is a customary component in Chinese medicine, and is characterized …
Antibiotic resistance breakers: can repurposed drugs fill the antibiotic discovery void?
D Brown - Nature reviews Drug discovery, 2015 - nature.com
Concern over antibiotic resistance is growing, and new classes of antibiotics, particularly
against Gram-negative bacteria, are needed. However, even if the scientific hurdles can be …
against Gram-negative bacteria, are needed. However, even if the scientific hurdles can be …