Berberine, an isoquinoline alkaloid isolated from the Chinese herb Coptis chinensis and
other Berberis plants, has a wide range of pharmacological properties. Berberine can be …

The AMP-activated protein kinase (AMPK) is a central regulator of multiple metabolic
pathways and may have therapeutic importance for treating obesity, insulin resistance, type …

Cardiovascular and metabolic diseases (CVMD) are the leading causes of death worldwide,
underscoring the urgent necessity to develop new pharmacotherapies. Berberine (BBR) is …

Skeletal muscle possesses a remarkable ability to adapt to various physiologic conditions.
AMPK is a sensor of intracellular energy status that maintains energy stores by fine-tuning …

Diabetes mellitus is a metabolic disorder that majorly affects the endocrine gland, and it is
symbolized by hyperglycemia and glucose intolerance owing to deficient insulin secretory …

The increased incidence of metabolic diseases (eg, diabetes and obesity) has seriously
affected human health and life safety worldwide. It is of great significance to find effective …

Abstract Context: Coptidis rhizome (CR), also known as Huanglian in Chinese, is the
rhizome of Coptis chinensis Franch., C. deltoidea CY Cheng et Hsiao, or C. teeta Wall …

Three main inflammatory signaling pathways include nuclear factor‐κB (NF‐κB), Janus
kinases/Signal transducer and activator of transcriptions (JAKs/STATs), and mitogen …

Berberine is an isoquinoline alkaloid present in several plants, including Coptis sp. and
Berberis sp. Berberine is a customary component in Chinese medicine, and is characterized …

Concern over antibiotic resistance is growing, and new classes of antibiotics, particularly
against Gram-negative bacteria, are needed. However, even if the scientific hurdles can be …