The pivotal link between ACE2 deficiency and SARS-CoV-2 infection
P Verdecchia, C Cavallini, A Spanevello… - European journal of …, 2020 - Elsevier
Abstract Angiotensin converting enzyme-2 (ACE2) receptors mediate the entry into the cell
of three strains of coronavirus: SARS-CoV, NL63 and SARS-CoV-2. ACE2 receptors are …
of three strains of coronavirus: SARS-CoV, NL63 and SARS-CoV-2. ACE2 receptors are …
COVID-19 and the cardiovascular system: implications for risk assessment, diagnosis, and treatment options
TJ Guzik, SA Mohiddin, A Dimarco, V Patel… - Cardiovascular …, 2020 - academic.oup.com
The novel coronavirus disease (COVID-19) outbreak, caused by SARS-CoV-2, represents
the greatest medical challenge in decades. We provide a comprehensive review of the …
the greatest medical challenge in decades. We provide a comprehensive review of the …
[HTML][HTML] Why does COVID-19 disproportionately affect older people?
AL Mueller, MS McNamara, DA Sinclair - Aging (albany NY), 2020 - ncbi.nlm.nih.gov
The severity and outcome of coronavirus disease 2019 (COVID-19) largely depends on a
patient's age. Adults over 65 years of age represent 80% of hospitalizations and have a 23 …
patient's age. Adults over 65 years of age represent 80% of hospitalizations and have a 23 …
Higher mortality of COVID-19 in males: sex differences in immune response and cardiovascular comorbidities
LA Bienvenu, J Noonan, X Wang… - Cardiovascular …, 2020 - academic.oup.com
The high mortality rate of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
infection is a critical concern of the coronavirus disease 2019 (COVID-19) pandemic …
infection is a critical concern of the coronavirus disease 2019 (COVID-19) pandemic …
Characteristics and outcomes of patients hospitalized for COVID-19 and cardiac disease in Northern Italy
RM Inciardi, M Adamo, L Lupi, DS Cani… - European heart …, 2020 - academic.oup.com
Aims To compare demographic characteristics, clinical presentation, and outcomes of
patients with and without concomitant cardiac disease, hospitalized for COVID-19 in Brescia …
patients with and without concomitant cardiac disease, hospitalized for COVID-19 in Brescia …
Association of cardiovascular disease and 10 other pre-existing comorbidities with COVID-19 mortality: A systematic review and meta-analysis
Background Estimating the risk of pre-existing comorbidities on coronavirus disease 2019
(COVID-19) mortality may promote the importance of targeting populations at risk to improve …
(COVID-19) mortality may promote the importance of targeting populations at risk to improve …
Hypertension, thrombosis, kidney failure, and diabetes: is COVID-19 an endothelial disease? A comprehensive evaluation of clinical and basic evidence
The symptoms most commonly reported by patients affected by coronavirus disease (COVID-
19) include cough, fever, and shortness of breath. However, other major events usually …
19) include cough, fever, and shortness of breath. However, other major events usually …
Interactions of coronaviruses with ACE2, angiotensin II, and RAS inhibitors—lessons from available evidence and insights into COVID-19
H Kai, M Kai - Hypertension Research, 2020 - nature.com
The rapid spread of a novel coronavirus, severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), has led to an ongoing pandemic of coronavirus disease 2019 (COVID-19) …
(SARS-CoV-2), has led to an ongoing pandemic of coronavirus disease 2019 (COVID-19) …
Age and multimorbidity predict death among COVID-19 patients: results of the SARS-RAS study of the Italian Society of Hypertension
Several factors have been proposed to explain the high death rate of the coronavirus
disease 2019 (COVID-19) outbreak, including hypertension and hypertension-related …
disease 2019 (COVID-19) outbreak, including hypertension and hypertension-related …
Renin–angiotensin–aldosterone system inhibitors and risk of Covid-19
HR Reynolds, S Adhikari, C Pulgarin… - … England Journal of …, 2020 - Mass Medical Soc
Background There is concern about the potential of an increased risk related to medications
that act on the renin–angiotensin–aldosterone system in patients exposed to coronavirus …
that act on the renin–angiotensin–aldosterone system in patients exposed to coronavirus …