Next-generation nanomaterials: advancing ocular anti-inflammatory drug therapy

J Wei, J Mu, Y Tang, D Qin, J Duan, A Wu - Journal of nanobiotechnology, 2023 - Springer
Ophthalmic inflammatory diseases, including conjunctivitis, keratitis, uveitis, scleritis, and
related conditions, pose considerable challenges to effective management and treatment …

Coenzyme Q10 Analogues: Benefits and Challenges for Therapeutics

JM Suárez-Rivero, CJ Pastor-Maldonado… - Antioxidants, 2021 - mdpi.com
Coenzyme Q10 (CoQ10 or ubiquinone) is a mobile proton and electron carrier of the
mitochondrial respiratory chain with antioxidant properties widely used as an antiaging …

Systemic conditions associated with severity of dry eye signs and symptoms in the dry eye assessment and management study

K Yu, V Bunya, M Maguire, P Asbell, GS Ying… - Ophthalmology, 2021 - Elsevier
Purpose Certain systemic conditions are reported to be risk factors for dry eye disease
(DED), but their associations with DED severity are not well studied. We evaluated whether …

Efficacy and safety of a water-free topical cyclosporine, 0.1%, solution for the treatment of moderate to severe dry eye disease: the ESSENCE-2 randomized clinical …

EK Akpek, DL Wirta, JE Downing, J Tauber… - JAMA …, 2023 - jamanetwork.com
Importance Dry eye disease (DED) is a common public health problem with significant
impact on vision-related quality of life and well-being of patients. Medications with rapid …

Ocular immune-related adverse events associated with immune checkpoint inhibitors in lung cancer

L Zhou, X Wei - Frontiers in Immunology, 2021 - frontiersin.org
Immune checkpoint inhibitors (ICIs) are novel immunotherapy-based drugs that have
become increasingly popular in the treatment of lung cancer. Researchers have recognized …

[HTML][HTML] The therapeutic use of quercetin in ophthalmology: Recent applications

L Zhao, H Wang, X Du - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Quercetin is a natural flavonol antioxidant found in various plant sources and food samples.
It is well known for its notable curative effects on the treatment of ophthalmic diseases due to …

NLRP12-and NLRC4-mediated corneal epithelial pyroptosis is driven by GSDMD cleavage accompanied by IL-33 processing in dry eye

H Chen, X Gan, Y Li, J Gu, Y Liu, Y Deng, X Wang… - The ocular …, 2020 - Elsevier
Purpose Dry eye disease (DED) is a common and multifactor-induced autoimmune ocular
surface disease. Environmental factors, such as desiccating stress (DS) and …

Provocation of dry eye disease symptoms during COVID-19 lockdown

N Neti, P Prabhasawat, C Chirapapaisan… - Scientific Reports, 2021 - nature.com
To assess the impact of COVID-19 lockdown measures on dry-eye symptoms in a
community-based population, a cross-sectional study was conducted during the first wave of …

Nutraceuticals: a promising therapeutic approach in ophthalmology

CR Castro-Castaneda, F Altamirano-Lamarque… - Nutrients, 2022 - mdpi.com
Oxidative stress represents one of the main factors driving the pathophysiology of multiple
ophthalmic conditions including presbyopia, cataracts, dry eye disease (DED), glaucoma …

Dry eye disease: early recognition with guidance on management and treatment for primary care family physicians

MA Verjee, AR Brissette, CE Starr - Ophthalmology and Therapy, 2020 - Springer
Primary care presentations of dry eye disease (DED) are common and pose a diagnostic
challenge due to the variety of symptoms and the absence of certainty for family …