Diet, physical activity or both for prevention or delay of type 2 diabetes mellitus and its associated complications in people at increased risk of developing type 2 …

B Hemmingsen, G Gimenez‐Perez… - Cochrane Database …, 2017 - cochranelibrary.com
Background The projected rise in the incidence of type 2 diabetes mellitus (T2DM) could
develop into a substantial health problem worldwide. Whether diet, physical activity or both …

[HTML][HTML] Prevention of type 2 diabetes by lifestyle changes: a systematic review and meta-analysis

M Uusitupa, TA Khan, E Viguiliouk, H Kahleova… - Nutrients, 2019 - mdpi.com
Prevention of type 2 diabetes (T2D) is a great challenge worldwide. The aim of this evidence
synthesis was to summarize the available evidence in order to update the European …

Long term maintenance of weight loss with non-surgical interventions in obese adults: systematic review and meta-analyses of randomised controlled trials

SU Dombrowski, K Knittle, A Avenell, V Araújo-Soares… - Bmj, 2014 - bmj.com
Objective To systematically review and describe currently available approaches to
supporting maintenance of weight loss in obese adults and to assess the evidence for the …

Tirzepatide for the treatment of adults with type 2 diabetes: an endocrine perspective

C De Block, C Bailey, C Wysham… - Diabetes, Obesity …, 2023 - Wiley Online Library
Tirzepatide is a novel glucose‐dependent insulinotropic polypeptide/glucagon‐like peptide
1 (GLP‐1) receptor agonist approved in the United States as an adjunct to diet and exercise …

Combined diet and physical activity promotion programs to prevent type 2 diabetes among persons at increased risk: a systematic review for the Community …

EM Balk, A Earley, G Raman, EA Avendano… - Annals of internal …, 2015 - acpjournals.org
Background: Trials have shown efficacy of rigorous diet and physical activity promotion
programs to reduce diabetes incidence and improve glycemic measures in adults at …

Lipotoxicity plays a key role in the development of both insulin resistance and muscle atrophy in patients with type 2 diabetes

RCR Meex, EE Blaak, LJC van Loon - Obesity Reviews, 2019 - Wiley Online Library
Insulin resistance and muscle mass loss often coincide in individuals with type 2 diabetes.
Most patients with type 2 diabetes are overweight, and it is well established that obesity and …

[HTML][HTML] The ABCD of obesity: an EASO position statement on a diagnostic term with clinical and scientific implications

G Frühbeck, L Busetto, D Dicker, V Yumuk… - Obesity facts, 2019 - karger.com
Obesity is a frequent, serious, complex, relapsing, and chronic disease process that
represents a major public health problem. The coining of obesity as an adiposity-based …

Combination of multiple low-risk lifestyle behaviors and incident type 2 diabetes: a systematic review and dose-response meta-analysis of prospective cohort studies

TA Khan, D Field, V Chen, S Ahmad, SB Mejia… - Diabetes …, 2023 - Am Diabetes Assoc
OBJECTIVE Combined low-risk lifestyle behaviors (LRLBs) have been associated with a
reduction in type 2 diabetes risk. This relationship has not been systematically quantified …

[HTML][HTML] Food sources of fat may clarify the inconsistent role of dietary fat intake for incidence of type 2 diabetes

U Ericson, S Hellstrand, L Brunkwall, CA Schulz… - The American journal of …, 2015 - Elsevier
Background: Dietary fats could affect glucose metabolism and obesity development and,
thereby, may have a crucial role in the cause of type 2 diabetes (T2D). Studies indicated that …

[HTML][HTML] Ectopic fat accumulation in distinct insulin resistant phenotypes; targets for personalized nutritional interventions

I Trouwborst, SM Bowser, GH Goossens… - Frontiers in …, 2018 - frontiersin.org
Cardiometabolic diseases are one of the leading causes for disability and mortality in the
Western world. The prevalence of these chronic diseases is expected to rise even further in …