Abstract Mitochondrial calcium (Ca2+) dynamics play critical roles in regulating vital
physiological conditions in the brain. Importantly, Mitochondria‐associated endoplasmic …

Myocardial ischemia reduces the supply of oxygen and nutrients to cardiomyocytes, leading
to an energetic crisis or cell death. Mitochondrial dysfunction is a decisive contributor to the …

Aim To explore the beneficial effects of L‐carnitine on cardiac microvascular dysfunction in
diabetic cardiomyopathy from the perspectives of mitophagy and mitochondrial integrity …

Cardiac fibrosis is characterized by the excessive deposition of extracellular matrix in the
myocardium with cardiac fibroblast activation, leading to chronic cardiac remodeling and …

Besides abstinence, no effective treatment exists for alcohol-related liver disease (ALD), a
dreaded consequence of alcohol abuse. In this study, we assessed the roles on ALD of dual …

Numerous mitochondrial abnormalities are reported to result from excessive inflammation
during endotoxemia. Prohibitin 2 (PHB2) and phosphoglycerate mutase 5 (Pgam5) have …

Apigenin is the active ingredient in Ludangshen. Although previous studies reported the
cardioprotective actions of apigenin against doxorubicin (Dox)-induced cardiomyopathy, the …

Background Septic cardiomyopathy (SCM), a common cardiovascular comorbidity of sepsis,
has emerged among the leading causes of death in patients with sepsis. SCM's …

We investigated the mechanism by which quercetin preserves mitochondrial quality control
(MQC) in cardiomyocytes subjected to ischemia–reperfusion stress. An enzyme‐linked …

Abstract Sirtuin-3 (Sirt3) deacetylates several mitochondrial proteins implicated into cerebral
ischemia/reperfusion (I/R) injury. The mitochondrial unfolded protein response (UPR mt) …