The membrane of the endoplasmic reticulum (ER) of nucleated human cells harbors the
protein translocon, which facilitates membrane integration or translocation of almost every …

Proteins targeted to the secretory pathway start their intracellular journey by being
transported across biological membranes such as the endoplasmic reticulum (ER). A central …

Recently, understanding of protein targeting to the endoplasmic reticulum (ER) was
expanded by the discovery of multiple pathways that function in parallel to the signal …

Protein transport into the endoplasmic reticulum (ER) is essential for all eukaryotic cells and
evolutionary related to protein transport into and across the cytoplasmic membrane of …

Proteins routed to the secretory pathway start their journey by being transported across
biological membranes, such as the endoplasmic reticulum. The essential nature of this …

Looking at the variety of the thousands of different polypeptides that have been focused on
in the research on the endoplasmic reticulum from the last five decades taught us one …

Tail-Anchored (TA) proteins are inserted into the endoplasmic reticulum (ER) membrane of
yeast cells via the posttranslational Guided Entry of Tail-Anchored protein (GET) pathway …

In human cells, approximately 30% of all polypeptides enter the secretory pathway at the
level of the endoplasmic reticulum (ER). This process involves cleavable amino-terminal …

Whilst the co-translational translocation of nascent proteins across the mammalian
endoplasmic reticulum (ER) is well defined, the capacity of this organelle for post …

Almost all cells use mRNA localization to establish spatial control of protein synthesis. One
of the best‐studied examples is the targeting and anchoring of mRNAs encoding secreted …