Mechanism of chromosomal mosaicism in preimplantation embryos and its effect on embryo development

X Zhang, PS Zheng - Journal of Assisted Reproduction and Genetics, 2024 - Springer
Aneuploidy is one of the main causes of miscarriage and in vitro fertilization failure. Mitotic
abnormalities in preimplantation embryos are the main cause of mosaicism, which may be …

Developmental perturbation in human embryos: Clinical and biological significance learned from time‐lapse images

K Ezoe, T Takahashi, T Miki… - Reproductive Medicine and …, 2024 - Wiley Online Library
Background Time‐lapse technology (TLT) has gained widespread adoption worldwide. In
addition to facilitating the undisturbed culture of embryos, TLT offers the unique capability of …

Trophectoderm cells of human mosaic embryos display increased apoptotic levels and impaired differentiation capacity: a molecular clue regarding their reproductive …

Á Martín, A Mercader, D Beltrán, A Mifsud… - Human …, 2024 - academic.oup.com
STUDY QUESTION Are there cell lineage-related differences in the apoptotic rates and
differentiation capacity of human blastocysts diagnosed as euploid, mosaic, and aneuploid …

The number of nuclei in compacted embryos, assessed by optical coherence microscopy, is a non-invasive and robust marker of mouse embryo quality

A Sobkowiak, M Fluks, E Kosyl… - Molecular Human …, 2024 - academic.oup.com
Optical coherence microscopy (OCM) visualizes nuclei in live, unlabeled cells. As most cells
are uninucleated, the number of nuclei in embryos may serve as a proxy of the cell number …

Time-lapse imaging of morula compaction for selecting high‐quality blastocysts: a retrospective cohort study

JK Park, Y Jeon, S Bang, JW Kim, IP Kwak… - Archives of Gynecology …, 2024 - Springer
Purpose Before blastocyst development, embryos undergo morphological and metabolic
changes crucial for their subsequent growth. This study aimed to investigate the relationship …

Time-lapse-Monitoring–Pro und Kontra

V Nordhoff, C Sibold, J Hirchenhain - Gynäkologische Endokrinologie, 2023 - Springer
Die medizinisch unterstützte Fortpflanzung („medically assisted reproduction “[MAR]) hat
sich seit den ersten erfolgreichen Schritten vor über 40 Jahren kontinuierlich …

[HTML][HTML]  Assessment of quadrivalent characteristics influencing chromosome segregation by analyzing human preimplantation embryos from reciprocal translocation …

ZN Tonyan, IL Puppo, AF Saifitdinova… - Comparative …, 2024 - ncbi.nlm.nih.gov
 Abstract Patterns of meiotic chromosome segregation were analyzed in cleavage stage and
blastocyst stage human embryos from couples with autosomal reciprocal translocations …

Correction to: The presence of partial compaction patterns is associated with lower rates of blastocyst formation, sub‑optimal morphokinetic parameters and poorer …

C Hur, V Nanavaty, M Yao, N Desai - Reproductive Biology and …, 2023 - ncbi.nlm.nih.gov
Correction to: The presence of partial compaction patterns is associated with lower rates of
blastocyst formation, sub‑optimal morphokinetic parameters and poorer morphologic grade …

Effects of embryo characteristics in frozen-thawed single euploid blastocyst transfers on pregnancy outcomes: a retrospective cohort study

G Özer, G Özkara - The European Research Journal, 2023 - dergipark.org.tr
Objectives: Our study examined the effects of the trophectoderm biopsy (TB) day and the
presence of necrotic foci (NF) or separate blastomeres (SB) within euploid embryos on in …

Samband mellan nukleära avvikelser i tvåcellsstadiet hos embryon efter assisterad befruktning och chans till graviditet och levande fött barn

H Sadullah - 2023 - diva-portal.org
Bakgrund Assisterad befruktning är en vanlig behandling för infertilitet, vilket innebär
oförmågan att bli gravid. Vid assisterad befruktning övervakas embryoutvecklingen med …