[PDF][PDF] Modulation of redox-sensitive transcription factors with polyphenols as pathogenetically grounded approach in therapy of systemic inflammatory response

V Kostenko, O Akimov, O Gutnik, H Kostenko… - Heliyon, 2023 - cell.com
One of the adverse outcomes of acute inflammatory response is progressing to the chronic
stage or transforming into an aggressive process, which can develop rapidly and result in …

Activation of Nrf2 pathway as a protective mechanism against oxidative stress-induced diseases: Potential of astaxanthin

ON Kanwugu, TV Glukhareva - Archives of Biochemistry and Biophysics, 2023 - Elsevier
Astaxanthin, a red-orange liposoluble carotenoid, has been the centre of considerable
attention in recent years for its numerous biological activities, notably its potent antioxidant …

Acrolein: Formation, health hazards and its controlling by dietary polyphenols

Y Zhou, W Jin, Q Wu, Q Zhou - Critical Reviews in Food Science …, 2023 - Taylor & Francis
Acrolein, a highly reactive toxic aldehyde, is a common dietary and environmental
contaminant which can also be generated endogenously. Exposure to acrolein has been …

[HTML][HTML] Seedless black Vitis vinifera polyphenols suppress hepatocellular carcinoma in vitro and in vivo by targeting apoptosis, cancer stem cells, and proliferation

NZ Shaban, WA Hegazy, MM Abu-Serie… - Biomedicine & …, 2024 - Elsevier
Hepatocellular carcinoma (HCC) is an aggressive tumor and one of the most challenging
cancers to treat. Here, we evaluated the in vitro and in vivo ameliorating impacts of seedless …

A Comparative Analysis of Chemical Constituents and Antioxidant Effects of Dendrobium fimbriatum Hook Fractions with Different Polarities

T Zhao, F Zheng, Y Liu, A Khan, Z Wang… - International Journal of …, 2023 - mdpi.com
The aim of this study was to investigate the chemical composition and antioxidant capacity of
various polar fractions obtained from Dendrobium fimbriatum Hook (DH). First, a 90 …

Neuroprotective Effects of a Novel Tetrapeptide SGGY from Walnut against H2O2-Stimulated Oxidative Stress in SH-SY5Y Cells: Possible Involved JNK, p38 and …

L Feng, Y Wu, J Wang, Y Han, J Huang, H Xu - Foods, 2023 - mdpi.com
SGGY, an antioxidant tetrapeptide identified from walnut protein hydrolysate in our previous
study, has been suggested to possess the potential to alleviate oxidative stress in cells. In …

Vitexin and isovitexin delayed ageing and enhanced stress-resistance through the activation of the SKN-1/Nrf2 signaling pathway

M Tao, R Li, T Xu, Z Zhang, D Zheng, Z Xia… - … Journal of Food …, 2023 - Taylor & Francis
Vitexin and isovitexin, as potential SKN-1/Nrf2 (SKN-1 is a homologous protein of
mammalian Nrf2) activators, extended lifespan and promoted healthspan in Caenorhabditis …

Synthesis of New Shogaol Analogues as NRF2 Activators and Evaluation of Their Anti-Inflammatory Activity, Modes of Action and Metabolic Stability

KK Mak, Z Shiming, R Sakirolla, MK Balijepalli… - Antioxidants, 2023 - mdpi.com
6-shogaol is a natural and the most potent bioactive vanilloid in dried Zingiber officinale
rhizomes. Many scientific studies have reported the diverse biological activities of 6-shogaol …