Contemporary medical management of peripheral artery disease

MP Bonaca, NM Hamburg, MA Creager - Circulation research, 2021 - Am Heart Assoc
Peripheral artery disease (PAD) is a manifestation of systemic atherosclerosis. Modifiable
risk factors including cigarette smoking, dyslipidemia, diabetes, poor diet quality, obesity …

[HTML][HTML] The role of the coagulation system in peripheral arterial disease: interactions with the Arterial Wall and its vascular microenvironment and implications for …

G Miceli, MG Basso, G Rizzo, C Pintus… - International Journal of …, 2022 - mdpi.com
Peripheral artery disease (PAD) is a clinical manifestation of atherosclerotic disease with a
large-scale impact on the economy and global health. Despite the role played by platelets in …

Rivaroxaban and aspirin in peripheral artery disease lower extremity revascularization: impact of concomitant clopidogrel on efficacy and safety

WR Hiatt, MP Bonaca, MR Patel, MR Nehler… - Circulation, 2020 - Am Heart Assoc
Background: The VOYAGER PAD trial (Vascular Outcomes Study of ASA Along With
Rivaroxaban in Endovascular or Surgical Limb Revascularization for Peripheral Artery …

Efficacy and safety of dual-pathway inhibition in patients with cardiovascular disease: a meta-analysis of 49 802 patients from 7 randomized trials

M Galli, D Capodanno, S Benenati… - European Heart …, 2022 - academic.oup.com
Aims Low-dose (LD) direct oral anticoagulants (DOACs) in adjunct to antiplatelet therapy,
known as dual-pathway inhibition (DPI), have been tested to prevent ischaemic events in …

Safety and efficacy of P2Y12 inhibitor monotherapy in patients undergoing percutaneous coronary interventions

M Galli, D Capodanno, F Andreotti, F Crea… - Expert opinion on …, 2021 - Taylor & Francis
Introduction: Antiplatelet therapy represents a key strategy for the prevention of thrombotic
complications in patients with both acute and chronic coronary syndromes, particularly those …

Switching from dual antiplatelet therapy with aspirin plus a P2Y12 inhibitor to dual pathway inhibition with aspirin plus vascular-dose rivaroxaban: the Switching Anti …

L Ortega-Paz, F Franchi, F Rollini… - Thrombosis and …, 2024 - thieme-connect.com
Background To date, there are no data on switching to dual pathway inhibition (DPI) patients
who have completed a guideline-recommended dual antiplatelet therapy (DAPT) regimen …

[HTML][HTML] Rivaroxaban in patients with symptomatic peripheral artery disease after lower extremity bypass surgery with venous and prosthetic conduits

N Govsyeyev, M Nehler, MS Conte, S Debus… - Journal of Vascular …, 2023 - Elsevier
Background Patients with peripheral artery disease (PAD) requiring lower extremity
revascularization (LER) have a high risk of adverse limb and cardiovascular events. The …

Antithrombotic Treatment in Coronary Artery Disease

G Siasos, V Tsigkou, E Bletsa… - Current …, 2023 - ingentaconnect.com
Coronary artery disease exhibits growing mortality and morbidity worldwide despite the
advances in pharmacotherapy and coronary intervention. Coronary artery disease is …

Dual pathway inhibition in patients with atherosclerotic disease: pharmacodynamic considerations and clinical implications

M Galli, F Franchi, F Rollini, L Ortega-Paz… - Expert review of …, 2023 - Taylor & Francis
Introduction The persistence of elevated rates of ischemic recurrences despite the use of
antiplatelet therapy among patients with atherosclerotic disease together with the …

Pharmacodynamic profiles of dual-pathway inhibition with or without clopidogrel versus dual antiplatelet therapy in patients with atherosclerotic disease

M Galli, F Franchi, F Rollini, L Been… - Thrombosis and …, 2022 - thieme-connect.com
Aim Inhibition of thrombin-mediated signaling processes using a vascular dose of
rivaroxaban in adjunct to antiplatelet therapy, known as dual-pathway inhibition (DPI) …