Marine mammals are indicator species of the Arctic ecosystem and an integral component of
the traditional Inuit diet. The potential neurotoxic effects of increased mercury (Hg) in beluga …

Stem cell-based in vitro test systems can recapitulate specific phases of human
development. In the UKK test system, human pluripotent stem cells (hPSCs) randomly …

Damage to the locus ceruleus has been implicated in the pathogenesis of a number of
neurological conditions. Locus ceruleus neurons accumulate toxic metals such as mercury …

There is a need to interpret neurotoxic studies to help deal with uncertainties surrounding
pregnant mothers, newborns and young children who must receive repeated doses of …

From an evolutionary perspective, the genes of enteric microbes transmitted reliably across
generations are nearly as much a part of the human organism as our own genes. Disruption …

Background Damage to the locus ceruleus, with a subsequent decrease of CNS
noradrenaline, occurs in a wide range of neurodegenerative, demyelinating and psychiatric …

Abstract Mercury (Hg) and lead (Pb) are known to be toxic non-radioactive elements, with
well-described neurotoxicology. Much evidence supports the implication of metals as …

Uranium (U) is naturally present in ambient air, water, and soil, and depleted uranium (DU)
is released into the environment via industrial and military activities. While the radiological …

Brains and blood of Alzheimer's disease (AD) patients have shown elevated mercury
concentrations, but potential involvement of mercury exposure in AD pathogenesis has not …

Alzheimer's disease (AD) is the leading cause of dementia in the elderly, affecting over 27
million people worldwide. AD represents a complex neurological disorder which is best …