Functional roles of magnetic nanoparticles for the identification of metastatic lymph nodes in cancer patients

Y Yan, Y Liu, T Li, Q Liang, A Thakur, K Zhang… - Journal of …, 2023 - Springer
Staging lymph nodes (LN) is crucial in diagnosing and treating cancer metastasis.
Biotechnologies for the specific localization of metastatic lymph nodes (MLNs) have …

[HTML][HTML] Myc oncogene: a druggable target for treating cancers with natural products

KI Chan, S Zhang, G Li, Y Xu, L Cui, Y Wang… - Aging and …, 2024 - ncbi.nlm.nih.gov
Various diseases, including cancers, age-associated disorders, and acute liver failure, have
been linked to the oncogene, MYC. Animal testing and clinical trials have shown that …

Phase separation of DDX21 promotes colorectal cancer metastasis via MCM5-dependent EMT pathway

H Gao, H Wei, Y Yang, H Li, J Liang, J Ye, F Zhang… - Oncogene, 2023 - nature.com
RNA binding proteins (RBPs) contributes to cancer progression, but the underlying
mechanism reminds unclear. Here, we find that DDX21, a representative RBP, is highly …

[HTML][HTML] Intermittent hypoxia mediates cancer development and progression through HIF-1 and miRNA regulation

G Moriondo, P Soccio, M Minoves, G Scioscia… - Archivos de …, 2023 - Elsevier
Introduction There is still a debate for the link between obstructive sleep apnoea (OSA) and
cancer. The mechanisms underlying this causality are poorly understood. Several miRNAs …

MYL9 expressed in cancer-associated fibroblasts regulate the immune microenvironment of colorectal cancer and promotes tumor progression in an autocrine …

S Deng, D Cheng, J Wang, J Gu, Y Xue, Z Jiang… - Journal of Experimental …, 2023 - Springer
Background The tumor microenvironment (TME) is an important factor that regulates the
progression of colorectal cancer (CRC). Cancer-associated fibroblasts (CAFs) are the main …

Establishment of cancer-associated fibroblasts-related subtypes and prognostic index for prostate cancer through single-cell and bulk RNA transcriptome

Y Qian, D Feng, J Wang, W Wei, Q Wei, P Han… - Scientific Reports, 2023 - nature.com
Current evidence indicate that cancer-associated fibroblasts (CAFs) play an important role in
prostate cancer (PCa) development and progression. In this study, we identified CAF-related …

[HTML][HTML] POSTN secretion by extracellular matrix cancer-associated fibroblasts (eCAFs) correlates with poor ICB response via macrophage chemotaxis activation of …

T You, H Tang, W Wu, J Gao, X Li, N Li, X Xu… - Aging and …, 2023 - ncbi.nlm.nih.gov
Immune checkpoint blockade (ICB) therapy has revolutionized cancer treatment, but its
clinical benefit is limited in advanced gastric cancer (GC). Cancer-associated fibroblasts …

Prolyl 4-hydroxylase subunit beta (P4HB) could serve as a prognostic and radiosensitivity biomarker for prostate cancer patients

D Feng, L Li, D Li, R Wu, W Zhu, J Wang, L Ye… - European Journal of …, 2023 - Springer
Background Prolyl 4-hydroxylase subunit beta (P4HB) has been reported as a suppressor in
ferroptosis. However, no known empirical research has focused on exploring relationships …

Decoding the Versatile Landscape of Autophagic Protein VMP1 in Cancer: A Comprehensive Review across Tissue Types and Regulatory Mechanisms

FJ Renna, CD Gonzalez, MI Vaccaro - International Journal of Molecular …, 2024 - mdpi.com
Autophagy, a catabolic process orchestrating the degradation of proteins and organelles
within lysosomes, is pivotal for maintaining cellular homeostasis. However, its dual role in …

microRNAs: Small molecules with a large impact on colorectal cancer

S Moazzendizaji, A Sevbitov, F Ezzatifar… - Biotechnology and …, 2022 - Wiley Online Library
Colorectal cancer (CRC) accounts for one of the main cancer‐related mortality and morbidity
worldwide. The molecular mechanisms of CRC development have been broadly …