The comet assay has become one of the methods of choice for the evaluation and
measurement of DNA damage. It is sensitive, quick to perform and relatively affordable for …

Since March 2013, animal use for cosmetics testing for the European market has been
banned. This requires a renewed view on risk assessment in this field. However, in other …

Placenta perfusion models are very effective when studying the placental mechanisms in
order to extrapolate to real‐life situations. The models are most often used to investigate the …

Nuclear abnormalities (micronuclei and meta-nuclear changes) have been used as
biomarkers to identify cell damages. As children are more vulnerable to the adverse effects …

To investigate the transplacental transport of pesticides, the pyrethroid cypermethrin and the
fungicide azoles, propiconazole and bitertanol were tested in the placental perfusion model …

The widespread use of agrochemicals results in the exposure of the general human
population, including children, to several of these chemicals simultaneously. In the present …

Este artículo examina de qué formas pueden defenderse conjuntamente los métodos de
investigación con animales no humanos, el rechazo de los métodos que no impliquen el …

The aim of this study was to evaluate genomic instability and cytotoxicity in buccal mucosa
cells of children living in abnormal conditions from Santos Sao Vicente estuary. The study …

Against the back-drop of the debate around a causative relationship between an escalating
mosquito-bourne Zika virus infection epidemic and the rise in incidence of microcephaly in …

Human exposure to parabens as a preservative used in personal care products is of
increasing concern, as there is evidence from in vivo and in vitro studies of hormone …