Seasonal influenza is a prevalent and serious annual illness resulting in widespread
morbidity and economic disruption throughout the population; the elderly and …

The timelines for developing vaccines against infectious diseases are lengthy, and often
vaccines that reach the stage of large phase 3 field trials fail to provide the desired level of …

Background Community-acquired pneumonia is a leading infectious cause of hospitalization
and death among US adults. Incidence estimates of pneumonia confirmed radiographically …

Background Incidence estimates of hospitalizations for community-acquired pneumonia
among children in the United States that are based on prospective data collection are …

Influenza virus vaccines are unique among currently licensed viral vaccines. The vaccines
designed to protect against seasonal influenza illness must be updated periodically in an …

Introduction: Rapid development and production of vaccines against emerging diseases
requires well established, validated, robust technologies to allow industrial scale production …

Purpose To assess the utility of “influenza-like illness”(ILI) and whether it appropriately tests
influenza vaccine effectiveness. Principal results The WHO and CDC definitions of …

Annual influenza vaccination is recommended for healthcare workers, but many do not
follow the recommendation. The objective of this study was to investigate the factors …

Background. Mismatch between circulating influenza B viruses (Yamagata and Victoria
lineages) and vaccine strains occurs frequently. Methods. In a randomized controlled trial …

Influenza is a highly contagious respiratory acute viral disease which imposes a very heavy
burden both in terms of epidemiology and costs, in the developed countries as well as in the …