Sarcoidosis is a systemic disease of unknown etiology defined by the presence of
noncaseating granulomatous inflammation that can cause organ damage and diminished …

Inflammation is the body's response to insults, which include infection, trauma, and
hypersensitivity. The inflammatory response is complex and involves a variety of …

Rationale New approaches to define factors underlying the immunopathogenesis of
pulmonary diseases including sarcoidosis and tuberculosis are needed to develop new …

Idiopathic pulmonary fibrosis (IPF) is a disabling disease of the lung parenchyma,
characterized by progressive accumulation of scar tissue and myofibroblast activation after …

Neurosarcoidosis is an uncommon but potentially serious manifestation of sarcoidosis.
While the cranial nerves are most frequently affected, neurosarcoidosis can involve other …

Sarcoidosis is a systemic granulomatous inflammatory disease of unknown etiology. It
affects the lungs in over 90% of patients yet extra-pulmonary and multi-organ involvement is …

Cardiac sarcoidosis is a potentially life-threatening condition characterized by formation of
granulomas in the heart, resulting in conduction disturbances, atrial and ventricular …

Background Sarcoidosis is a poorly understood chronic inflammatory condition. Infiltration of
affected organs by lymphocytes is characteristic of sarcoidosis, however previous reports …

The study of human pulmonary immunity against Mycobacterium tuberculosis (M. tb)
provides a unique window into the biological interactions between the human host and M. tb …

Sarcoidosis is a multisystem, T-helper 1 (Th1) cell biased granulomatous disorder that
develops in genetically predisposed individuals who are exposed to yet unknown …