Mitochondria play a key role in both health and disease. Their function is not limited to
energy production but serves multiple mechanisms varying from iron and calcium …

As the organ with the highest demand for oxygen, the brain has a poor tolerance to ischemia
and hypoxia. Despite severe ischemia/hypoxia induces the occurrence and development of …

This review is devoted to the phenomenon of intermittent hypoxic training and is aimed at
drawing the attention of researchers to the necessity of studying the mechanisms mediating …

New Findings What is the topic of this review? Remote ischaemic preconditioning (RIPC)
and hypoxic preconditioning as novel therapeutic approaches for cardiac and …

Intermittent hypoxic training (IHT) is a discrete cost-effective method for improving athletic
performance and high altitude acclimatization. Unfortunately, IHT protocols widely vary in …

Adolescence is a period of multiple changes where social behaviors influence interpersonal‐
relations. Adolescents live new experiences, including alcohol consumption which has …

Background: On the one hand, hypoxic exposure may result in progressive brain
metabolism disturbance, causing subsequent cognitive impairments. On the other hand, it …

Withdrawal from ethanol dependence has been associated with heightened anxiety and
reduced expression of Brain-derived neurotropic factor which promotes the synaptic …

The protective effect of intermittent hypoxia (IH) preconditioning against oxidative injury in
hepatic cells was investigated and the involvement of the PINK1/Parkin-mediated mitophagy …

Isolated exposure to intermittent hypoxia and permissive hypercapnia activates signaling
mechanisms that induce ultrastructural changes in mitochondria and endoplasmic reticulum …