[HTML][HTML] Devilishly radical NETwork in COVID-19: Oxidative stress, neutrophil extracellular traps (NETs), and T cell suppression

G Schönrich, MJ Raftery, Y Samstag - Advances in biological regulation, 2020 - Elsevier
Abstract Pandemic coronavirus disease 2019 (COVID-19) is caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) and poses an unprecedented challenge …

Thromboembolic events and Covid-19

A Ribes, F Vardon-Bounes, V Mémier, M Poette… - Advances in biological …, 2020 - Elsevier
The novel Corona virus infection (Covid-19) first identified in China in December 2019 has
rapidly progressed in pandemic leading to significant mortality and unprecedented …

[HTML][HTML] Increased number of pulmonary megakaryocytes in COVID-19 patients with diffuse alveolar damage: an autopsy study with clinical correlation and review of …

MF Valdivia-Mazeyra, C Salas, JM Nieves-Alonso… - Virchows Archiv, 2021 - Springer
Pulmonary megakaryocytes participate in the pathogenesis of lung damage, particularly in
acute lung injury. Although megakaryocytes are not mentioned as a characteristic histologic …

Platelet activation and partial desensitization are associated with viral xenophagy in patients with severe COVID-19

C Garcia, J Au Duong, M Poëtte, A Ribes… - Blood …, 2022 - ashpublications.org
Mild thrombocytopenia, changes in platelet gene expression, enhanced platelet
functionality, and presence of platelet-rich thrombi in the lung have been associated with …

[HTML][HTML] On the role of platelet-generated amyloid beta peptides in certain amyloidosis health complications

M Inyushin, A Zayas-Santiago, L Rojas… - Frontiers in …, 2020 - frontiersin.org
As do many other immunity-related blood cells, platelets release antimicrobial peptides that
kill bacteria, fungi, and even certain viruses. Here we review the literature suggesting that …

[HTML][HTML] Pharmacological management of COVID-19 patients with ARDS (CARDS): a narrative review

MG Matera, P Rogliani, L Calzetta, M Cazzola - Respiratory medicine, 2020 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) is highly infectious. It has been highlighted
that if not expertly and individually managed with consideration of the vasocentric features, a …

[HTML][HTML] Thrombosis and coagulopathy in COVID-19: current understanding and implications for antithrombotic treatment in patients treated with percutaneous …

H Liu, Z Wang, H Sun, T Teng, Y Li, X Zhou… - Frontiers in …, 2021 - frontiersin.org
Coronavirus disease 2019 (COVID-19), a respiratory syndrome, is a global pandemic.
Therefore, there is an urgent need to explore mechanisms implicated in the pathogenesis of …

[HTML][HTML] Antiplatelet therapy for acute respiratory distress syndrome

CM Chen, HC Lu, YT Tung, W Chen - Biomedicines, 2020 - mdpi.com
Acute respiratory distress syndrome (ARDS) is a common and devastating syndrome that
contributes to serious morbidities and mortality in critically ill patients. No known …

Recapitulation of human pathophysiology and identification of forensic biomarkers in a translational model of chlorine inhalation injury

S Achanta, MA Gentile, CJ Albert… - … of Physiology-Lung …, 2024 - journals.physiology.org
Chlorine gas (Cl2) has been repeatedly used as a chemical weapon, first in World War I and
most recently in Syria. Life-threatening Cl2 exposures frequently occur in domestic and …

Targeting SELPLG/P‐selectin glycoprotein ligand 1 in preclinical ARDS: Genetic and epigenetic regulation of the SELPLG promoter

X Sun, S Sammani, M Hufford, BL Sun… - Pulmonary …, 2023 - Wiley Online Library
We previously identified a missense single nucleotide polymorphism rs2228315 (G> A,
Met62Ile) in the selectin‐P‐ligand gene (SELPLG), encoding P‐selectin glycoprotein ligand …