Quantitative functional normal data should be a prerequisite before applying SPECT in
murine models of cardiac disease. Therefore, we investigated the capability of in vivo …

Background Defective copper regulation is implicated as a causative mechanism of organ
damage in diabetes. Treatment with trientine, a divalent-copper-selective chelator, improves …

Radiotracer kinetic modeling in small animals with PET allows absolute quantification of
physiologic and biochemical processes in vivo. It requires blood and tissue tracer …

Different animal models of estrogen positive tumors (ER+) were evaluated for their suitability
to follow tumor response after various treatment protocols, using small animal positron …

We sought to develop a practical, reproducible and clinically translatable method of
radiolabeling serum albumins with fluorine-18 for use as a PET blood pool imaging agent in …

The interest in small animal models of human diseases has generated a need to design a
computed tomography (CT) system that operates at a microscopic level. It is particularly …

Background—Aortic valve regurgitation (AR) is a volume-overload disease causing severe
eccentric left ventricular (LV) hypertrophy and eventually heart failure. There is currently no …

The LabPET II is a new positron emission tomography technology platform designed to
achieve submillimetric spatial resolution imaging using fully pixelated avalanche …

Aims Dual therapy comprising G-CSF for mobilization of bone marrow-derived progenitor
cells (BMPCs), with simultaneous pharmacological inhibition of dipeptidylpeptidase-IV for …

Acute myocardial infarction (AMI) research relies increasingly on small animal models and
noninvasive imaging methods such as MRI, single‐photon emission computed tomography …