Positron emission tomography in the assessment of left ventricular function in healthy rats: a comparison of four imaging methods

A Todica, G Böning, S Lehner, E Weidl… - Journal of Nuclear …, 2013 - Springer
Objective To measure left ventricular (LV) function parameters in heart of healthy rats by
three different positron emission tomography (PET) imaging techniques and by magnetic …

The assessment of left ventricular volume and function in gated small animal 18F-FDG PET/CT imaging: a comparative study of three commercially available software …

MJ Zacherl, A Simenhandra, M Lindner, P Bartenstein… - EJNMMI research, 2023 - Springer
Background Several software tools have been developed for gated PET imaging that use
distinct algorithms to analyze tracer uptake, myocardial perfusion, and left ventricle volumes …

Endurance training or beta-blockade can partially block the energy metabolism remodeling taking place in experimental chronic left ventricle volume overload

D Lachance, W Dhahri, MC Drolet, É Roussel… - BMC cardiovascular …, 2014 - Springer
Background Patients with chronic aortic valve regurgitation (AR) causing left ventricular (LV)
volume overload can remain asymptomatic for many years despite having a severely dilated …

Detection of cardiac apoptosis by [18F]ML-10 in a mouse model of permanent LAD ligation

M Fischer, J Olivier, S Lindner, MJ Zacherl… - Molecular Imaging and …, 2022 - Springer
Purpose The loss of viable cardiac cells and cell death by myocardial infarction (MI) is still a
significant obstacle in preventing deteriorating heart failure. Imaging of apoptosis, a defined …

In Vivo Monitoring of Parathyroid Hormone Treatment after Myocardial Infarction in Mice with [68Ga]Annexin A5 and [18F]Fluorodeoxyglucose Positron Emission …

S Lehner, A Todica, Y Vanchev, C Uebleis… - Molecular …, 2014 - journals.sagepub.com
[68Ga] Annexin A5 positron emission tomography (PET) reveals the externalization of
phosphatidylserine as a surrogate marker for apoptosis. We tested this technique for therapy …

Automatic Quantitative Assessment for Diagnostic and Therapeutic Response in Rodent Myocardial Infarct Model

K Kim, YJ Lee, MH Kim, BH Byun, SK Woo - Biomedicines, 2024 - mdpi.com
The purpose of this study was to investigate the most appropriate methodological approach
for the automatic measurement of rodent myocardial infarct polar map using histogram …

Resident and recruited macrophages differentially contribute to cardiac healing after myocardial ischemia

T Weinberger, M Denise, M Joppich, M Fischer… - Elife, 2024 - elifesciences.org
Cardiac macrophages are heterogenous in phenotype and functions, which has been
associated with differences in their ontogeny. Despite extensive research, our …

Erroneous cardiac ECG-gated PET list-mode trigger events can be retrospectively identified and replaced by an offline reprocessing approach: first results in rodents

G Böning, A Todica, A Vai, S Lehner… - Physics in Medicine …, 2013 - iopscience.iop.org
The assessment of left ventricular function, wall motion and myocardial viability using
electrocardiogram (ECG)-gated [18 F]-FDG positron emission tomography (PET) is widely …

Comparison of transient and permanent LAD ligation in mice using 18F-FDG PET imaging

M Fischer, T Weinberger, D Messerer… - Annals of Nuclear …, 2022 - Springer
Objective Animal models for myocardial injuries represent important cornerstones in
cardiovascular research to monitor the pathological processes and therapeutic approaches …

Monitoring left ventricular dilation in mice with PET

L Stegger, KP Schäfers, U Flögel… - Journal of Nuclear …, 2005 - Soc Nuclear Med
Molecular imaging by small-animal PET is an important noninvasive means to phenotype
transgenic mouse models in vivo. When investigating pathologies of the left ventricular (LV) …