[HTML][HTML] 67Cu Production Capabilities: A Mini Review

L Mou, P Martini, G Pupillo, I Cieszykowska, CS Cutler… - Molecules, 2022 - mdpi.com
Is the 67Cu production worldwide feasible for expanding preclinical and clinical studies?
How can we face the ingrowing demands of this emerging and promising theranostic …

Purification of Copper Radioisotopes for Medical Applications: Chromatographic Methods and Challenges

AI Fonseca, SJC Do Carmo, I Hrynchak… - Separation & …, 2023 - Taylor & Francis
Copper radioisotopes are gaining increasing significance for medical use in recent years for
both diagnostic and therapeutic applications. To answer the growing clinical demand, fast …

A facile strategy for synthesis of a broad palette of intrinsically radiolabeled chitosan nanoparticles for potential use in cancer theranostics

G Gaikwad, N Rohra, C Kumar, S Jadhav… - Journal of Drug Delivery …, 2021 - Elsevier
The conventional, chelator-based techniques used for radiolabelling of nanoparticles
possess certain shortcomings due to their inherent limitations related to coordination …

[HTML][HTML] Microfluidic solvent extraction of no-carrier-added 64Cu from irradiated Zn target for radiopharmaceutical preparation

R Chakravarty, N Sen, S Patra, A Rajeswari… - Chemical Engineering …, 2023 - Elsevier
Microfluidics based liquid-liquid extraction is emerging as an enabling and powerful
technology in radiochemical separations of medically important radioisotopes. In this study …

[HTML][HTML] Surface engineered Fe 3 O 4 nanomagnets for pH-responsive delivery of gemcitabine hydrochloride and in vivo tracking by radiolabeling

B Dutta, SB Shelar, KC Barick, P Shetty… - Materials …, 2023 - pubs.rsc.org
Gemcitabine, a well-known nucleoside analogue, has shown tremendous potential against
solid tumors. However, its clinical use is limited due to its poor biological half-life and low …

Biochemical separation of Cetuximab-Fab from papain-digested antibody fragments and radiolabeling with 64Cu for potential use in radioimmunotheranostics

R Chakravarty, N Rohra, S Jadhav, HD Sarma… - Applied Radiation and …, 2023 - Elsevier
Engineered Fab fragments of monoclonal antibodies (mAbs) after radiolabeling with suitable
radiometals have the potential to play a key role in personalized radioimmunotheranostics of …

Purification process for the preparation of non-carrier added copper-64

D Pipes, L Radford, W Uhland, B Regna… - US Patent …, 2024 - Google Patents
Compositions comprising high levels of high specific activity copper-64, and process for
preparing said compositions. The compositions comprise from about 2 Ci to about 15 Ci of …