[HTML][HTML] Neurofilament proteins as biomarkers to monitor neurological diseases and the efficacy of therapies
Biomarkers of neurodegeneration and neuronal injury have the potential to improve
diagnostic accuracy, disease monitoring, prognosis, and measure treatment efficacy …
diagnostic accuracy, disease monitoring, prognosis, and measure treatment efficacy …
The multifaceted role of neurofilament light chain protein in non-primary neurological diseases
The advancing validation and exploitation of CSF and blood neurofilament light chain
protein as a biomarker of neuroaxonal damage has deeply changed the current diagnostic …
protein as a biomarker of neuroaxonal damage has deeply changed the current diagnostic …
Axonal marker neurofilament light predicts long-term outcomes and progressive neurodegeneration after traumatic brain injury
Axonal injury is a key determinant of long-term outcomes after traumatic brain injury (TBI) but
has been difficult to measure clinically. Fluid biomarker assays can now sensitively quantify …
has been difficult to measure clinically. Fluid biomarker assays can now sensitively quantify …
Time course and diagnostic utility of NfL, tau, GFAP, and UCH-L1 in subacute and chronic TBI
P Shahim, A Politis, A Van Der Merwe, B Moore… - Neurology, 2020 - AAN Enterprises
Objective To determine whether neurofilament light (NfL), glial fibrillary acidic protein
(GFAP), tau, and ubiquitin C-terminal hydrolase-L1 (UCH-L1) measured in serum relate to …
(GFAP), tau, and ubiquitin C-terminal hydrolase-L1 (UCH-L1) measured in serum relate to …
[HTML][HTML] Role of SARS-CoV-2 spike-protein-induced activation of microglia and mast cells in the pathogenesis of neuro-COVID
TC Theoharides, D Kempuraj - Cells, 2023 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus
disease 2019 (COVID-19). About 45% of COVID-19 patients experience several symptoms a …
disease 2019 (COVID-19). About 45% of COVID-19 patients experience several symptoms a …
What tests and measures accurately diagnose persisting post-concussive symptoms in children, adolescents and adults following sport-related concussion? A …
Objective To determine what tests and measures accurately diagnose persisting post-
concussive symptoms (PPCS) in children, adolescents and adults following sport-related …
concussive symptoms (PPCS) in children, adolescents and adults following sport-related …
[HTML][HTML] Point-of-care electrochemical testing of biomarkers involved in inflammatory and inflammatory-associated medical conditions
Recent years have shown that the diagnosis and monitoring of biomarkers involved in
inflammatory-associated medical conditions such as cancer, neurological disorders, viral …
inflammatory-associated medical conditions such as cancer, neurological disorders, viral …
Post-acute blood biomarkers and disease progression in traumatic brain injury
There is substantial interest in the potential for traumatic brain injury to result in progressive
neurological deterioration. While blood biomarkers such as glial fibrillary acid protein …
neurological deterioration. While blood biomarkers such as glial fibrillary acid protein …
Role of biomarkers and emerging technologies in defining and assessing neurobiological recovery after sport-related concussion: a systematic review
Objective Determine the role of fluid-based biomarkers, advanced neuroimaging, genetic
testing and emerging technologies in defining and assessing neurobiological recovery after …
testing and emerging technologies in defining and assessing neurobiological recovery after …
A framework to advance biomarker development in the diagnosis, outcome prediction, and treatment of traumatic brain injury
EA Wilde, IB Wanner, K Kenney, J Gill… - Journal of …, 2022 - liebertpub.com
Multi-modal biomarkers (eg, imaging, blood-based, physiological) of unique traumatic brain
injury (TBI) endophenotypes are necessary to guide the development of personalized and …
injury (TBI) endophenotypes are necessary to guide the development of personalized and …