International consensus statement on allergy and rhinology: olfaction

ZM Patel, EH Holbrook, JH Turner… - International forum of …, 2022 - Wiley Online Library
Background The literature regarding clinical olfaction, olfactory loss, and olfactory
dysfunction has expanded rapidly over the past two decades, with an exponential rise in the …

Olfactory bulb involvement in neurodegenerative diseases

J Attems, L Walker, KA Jellinger - Acta neuropathologica, 2014 - Springer
Olfactory dysfunction is a common and early symptom of many neurodegenerative diseases,
particularly of Parkinson's disease and other synucleinopathies, Alzheimer's disease (AD) …

Lateralisation in Parkinson disease

P Riederer, KA Jellinger, P Kolber, G Hipp… - Cell and tissue …, 2018 - Springer
Asymmetry of dopaminergic neurodegeneration and subsequent lateralisation of motor
symptoms are distinctive features of Parkinson's disease compared to other forms of …

[HTML][HTML] The interplay between alpha-synuclein clearance and spreading

T Lopes da Fonseca, A Villar-Piqué, TF Outeiro - Biomolecules, 2015 - mdpi.com
Parkinson's Disease (PD) is a complex neurodegenerative disorder classically
characterized by movement impairment. Pathologically, the most striking features of PD are …

Mild cognitive impairment in patients with Parkinson's disease is associated with increased cortical degeneration

A Hanganu, C Bedetti, T Jubault, JF Gagnon… - Movement …, 2013 - Wiley Online Library
Mild cognitive impairment (MCI) can occur early in the course of Parkinson's disease (PD),
and its presence increases the risk of developing dementia. Determining the cortical …

Patterns of olfactory functional networks in Parkinson's disease dementia and Alzheimer's dementia

YH Lee, Y Bak, C Park, SJ Chung, HS Yoo, K Baik… - Neurobiology of …, 2020 - Elsevier
Hyposmia is common in Alzheimer's dementia (AD) and Parkinson's disease dementia
(PDD). We evaluated the pattern of olfactory functional connectivity (FC) in AD and PDD to …

[HTML][HTML] Dopamine increases the intrinsic excitability of parvalbumin-expressing fast-spiking cells in the piriform cortex

Y Potts, JM Bekkers - Frontiers in cellular neuroscience, 2022 - frontiersin.org
The piriform cortex (PCx) is essential for the adaptive processing of olfactory information.
Neuromodulatory systems, including those utilizing serotonin, acetylcholine, noradrenaline …

[HTML][HTML] A study of neural activity and functional connectivity within the olfactory brain network in Parkinson's disease

C Georgiopoulos, ST Witt, S Haller, N Dizdar… - NeuroImage: Clinical, 2019 - Elsevier
Olfactory dysfunction is an early manifestation of Parkinson's disease (PD). The present
study aimed to illustrate potential differences between PD patients and healthy controls in …

Correlation between progressive changes in piriform cortex and olfactory performance in early Parkinson's disease

X Wu, C Yu, F Fan, K Zhang, C Zhu, T Wu, K Li… - European …, 2011 - karger.com
Objectives: The mechanism underlying olfactory dysfunction in Parkinson's disease (PD)
remains unknown. The current study aims to investigate the relationship between sequential …

[HTML][HTML] Social defeat drives hyperexcitation of the piriform cortex to induce learning and memory impairment but not mood-related disorders in mice

H Wang, F Li, X Zheng, L Meng, M Chen, Y Hui… - Translational …, 2022 - nature.com
Clinical studies have shown that social defeat is an important cause of mood-related
disorders, accompanied by learning and memory impairment in humans. The mechanism of …