Osteoarthritis (OA) is endemic throughout the world. An estimated 30.8 million adults in the
United States and 300 million individuals worldwide are living with OA. 1, 2 It is the leading …

The purpose of this article is to provide a synopsis of the current medical understanding of
knee osteoarthritis. We describe the prevalence, causes and associated risk factors …

Ageing-associated changes that affect articular tissues promote the development of
osteoarthritis (OA). Although ageing and OA are closely linked, they are independent …

Metabolism is important for cartilage and synovial joint function. Under adverse
microenvironmental conditions, mammalian cells undergo a switch in cell metabolism from a …

Low back pain is a leading cause of disability worldwide. Intervertebral disc (IVD)
degeneration is often associated with low back pain but is sometimes asymptomatic. IVD …

Introduction Osteoarthritis (OA) is one of the most common forms of arthritis. There is
accumulating evidence to suggest that OA is an inflammatory disease of the entire synovial …

It is well accepted that aging is an important contributing factor to the development of
osteoarthritis (OA). The mechanisms responsible appear to be multifactorial and may …

Osteoarthritis (OA) is a highly prevalent whole-joint disease that causes disability and pain
and affects a patient's quality of life. However, currently, there is a lack of effective early …

The objective of this article is to deliver a concise up-to-date review on hip osteoarthritis. We
describe the epidemiology (disease distribution), etiologies (associated risk factors) …

Objectives To investigate the prevalence of osteoarthritis (OA) in patients with diabetes
mellitus (DM) and prevalence of DM in patients with OA and whether OA and DM are …