Abstract The Toxicology Forum convened an international state-of-the-science workshop
Assessing Chemical Carcinogenicity: Hazard Identification, Classification, and Risk …

In contrast to genotoxic carcinogens, there are currently no internationally agreed upon
regulatory tools for identifying non-genotoxic carcinogens of human relevance. The rodent …

Rodent cancer bioassays have been long-required studies for regulatory assessment of
human cancer hazard and risk. These studies use hundreds of animals, are resource …

Use of molecular data in human and ecological health risk assessments of industrial
chemicals and agrochemicals has been anticipated by the scientific community for many …

Carcinogenicity testing plays an essential role in identifying carcinogens in environmental
chemistry and drug development. However, it is a time-consuming and label-intensive …

Determining environmental chemical carcinogenicity is urgently needed as humans are
increasingly exposed to these chemicals. In this study, we developed a hybrid neural …

The application of in vitro biological assays as new approach methodologies (NAMs) to
support grouping of UVCB (unknown or variable composition, complex reaction products …

Identifying a toxicity point of departure (POD) is a required step in human health risk
characterization of crop protection molecules, and this POD has historically been derived …

Read-across is a data gap filling technique utilized to predict the toxicity of a target chemical
using data from similar analogues. Recent efforts such as Generalized Read-Across …

For a pharmaceutical drug, carcinogenicity testing occurs in rodents to identify its
tumorigenic potential to allow assessment of the risk from its use in humans. Testing takes …