Astrocytes in selective vulnerability to neurodegenerative disease

TS Zimmer, AL Orr, AG Orr - Trends in neurosciences, 2024 - cell.com
Selective vulnerability of specific brain regions and cell populations is a hallmark of
neurodegenerative disorders. Mechanisms of selective vulnerability involve neuronal …

Mechanisms of activation of brain's drainage during sleep: the nightlife of astrocytes

D Postnov, O Semyachkina-Glushkovskaya… - Cells, 2023 - mdpi.com
The study of functions, mechanisms of generation, and pathways of movement of cerebral
fluids has a long history, but the last decade has been especially productive. The proposed …

An 840 kb distant upstream enhancer is a crucial regulator of catecholamine‐dependent expression of the Bdnf gene in astrocytes

A Avarlaid, EE Esvald, I Koppel, A Parkman… - Glia, 2024 - Wiley Online Library
Brain‐derived neurotrophic factor (BDNF) plays a fundamental role in the developing and
adult nervous system, contributing to neuronal survival, differentiation, and synaptic …

Circadian mechanisms in brain fluid biology

VS Vizcarra, RM Fame, LM Hablitz - Circulation Research, 2024 - Am Heart Assoc
The brain is a complex organ, fundamentally changing across the day to perform basic
functions like sleep, thought, and regulating whole-body physiology. This requires a …

Astrocytes as Drivers and Disruptors of Behavior: New Advances in Basic Mechanisms and Therapeutic Targeting

D Barnett, K Bohmbach, V Grelot, A Charlet… - Journal of …, 2023 - Soc Neuroscience
Astrocytes are emerging as key regulators of cognitive function and behavior. This review
highlights some of the latest advances in the understanding of astrocyte roles in different …

Astrocytes: new evidence, new models, new roles

A Brazhe, A Verisokin, D Verveyko, D Postnov - Biophysical Reviews, 2023 - Springer
Astrocytes have been in the limelight of active research for about 3 decades now. Over this
period, ideas about their function and role in the nervous system have evolved from simple …

The Role of Glial Cells in Neurobiology and Prion Neuropathology

A Hay, K Popichak, J Moreno, M Zabel - Cells, 2024 - mdpi.com
Prion diseases are rare and neurodegenerative diseases that are characterized by the
misfolding and infectious spread of the prion protein in the brain, causing progressive and …

[HTML][HTML] Astrocytic calcium waves: unveiling their roles in sleep and arousal modulation

E Wu, D Qi, D Nizamutdinov… - Neural Regeneration …, 2024 - journals.lww.com
Neuron-astrocyte interactions are vital for the brain's connectome. Understanding astrocyte
activities is crucial for comprehending the complex neural network, particularly the …

Norepinephrine–Astrocyte Signaling Regulates Cortical State Homeostasis

Y Li, L Li, Y Wang, X Li, Z Chen - Neuroscience Bulletin, 2024 - Springer
Accepted: 4 February 2024© Center for Excellence in Brain Science and Intelligence
Technology, Chinese Academy of Sciences 2024 by Reitman et al. discovered that …

Morphotype-specific calcium signaling in human microglia

S Nevelchuk, B Brawek, N Schwarz… - bioRxiv, 2024 - biorxiv.org
Key functions of calcium signaling in rodent microglia include monitoring the brain state or
the surrounding neuronal activity and sensing the danger or damage in their vicinity …